378 VEGETABLE DRUGS 



nerved cotyledons project. It is inodorous and persistently 

 bitter. 



Constituents. — Two alkaloids. 1. Strychnine, 0.2-0.6 per 

 cent. 2. Brucine (CogHjeNjOJ, 0.5-1.0 per cent. Similar in 

 action to strychnine, but weaker and slower. Both alkaloids 

 exist in combination with igasuric acid. Brucine occurs in 

 rectangular octohedral crystals ; is soluble in alcohol, in 

 7 parts of chloroform, and possesses a bitter taste. With 

 sulphuric and nitric acids a beautiful blood-red color is 

 developed. 



Dose.—R, & C, 3i.-ii. (4.-8.); Sh., gr.xx.-xl. (1.3-2.6);, 

 Sw., gr.x.-xx. (.6-1.3); D., gr.i.-ii. (.06-.12). 



PREPARATIONS. 



Extr actum Nucis VomiccB. Extract of Nux Vomica. (U. S. & B. P.) 

 Made by maceration with alcohol, water and acetic acid; percola- 

 tion with alcohol and water; distillation to remove alcohol, and evapo- 

 ration. The liquid extract is treated with ether, and sufficient sugar of 

 milk is added to make the contents of alkaloids equal to 15 per cent, of 

 of the dry extract. (U. S. P. ) 



Dose.— H. & C, gr.vii.-xv. (.5-1.) ; Sh., gr.ii.ss.-v. (.15-.3); Sw.^ 

 gr.i.-ii. (.06-.12); D., ^r.H (.008-.016). 



Extractum Nucis Vomicce Fliiiduin. Fluid Extract of Nux Vomica. 



(U. S. P.) 

 Made by digestion and percolation with alcohol, water and acetic 

 acid. The alcohol is distilled off and the solution evaporated. Alcohol 

 and water are added so that 100 Cc. of the fluid extract shall contain 

 Gm. 1.5 of total alkaloids. 



Dose.— H. &C., 3i.-ii. (4.-8.); Sh., ttixx.-xxx. (1.3-2.); Sw., nx.- 

 XX. (6-1.3); D., Tn,i..ii. (.06-.12). 



Tinctura Nucis Vomicce. Ticture of Nux Vomica. (U. S. & B. P.) 

 Made by solution of the extract of nux vomica, 20, in alcohol, and 

 water to make 1,000. (U. S. P.) 

 Dose,— D., mv.-x. (.3-.6). 



Strychnina. Strychnine. G,, H,, N, O,. (U. S. & B. P.) 



An alkaloid obtained from nux vomica, and also obtain- 

 able from other plants of the natural order Loganiaceae. 



