416 VEGETABLE DRUGS 



decomposition of pilocarpine, which it resembles in action, 

 but is weaker. It is soluble in alcohol. 4. Jaborandine is 

 another alkaloid resulting from the decomposition of pilo- 

 carpine, and is similar to atropine. These atropine-like 

 principles are never present in sufficient quantity to wholly 

 antagonize the predominant action of pilocarpine in jabor- 

 andi. 5. A peculiar acid. 6. A volatile oil. 



Dose.—K. & C, 3ii.-iv..(8.-15.); Sh. & Sw., 3 «3.-i. (2.-4.); 

 D.,gr.v.-3i. (.3-4.). 



PREPARATIONS. 



Extractum Pilocarpi Fluidum. Fluid Extract of Pilocarpus. 

 (U. S. P.) 



Made by maceration and percolation with diluted alcohol, and 

 evaporation, so that 1 Cc. = 1 Gm. of the crude drug. 



Dose.-n. & C, 3ii-iv. (8.-15.); Sh. & Sw., 3 ss.-i. (2.-4.); D., 

 mv.- 3 i. (.3-4.). 



Extractum Jahorandi. (B. P.) 

 Dose.— H., gr.xl.- 3 i.ss. (2.6-6.); D. , gr.ii.-x (. 12-.6). 



PiLOCARPiNiE Hydrochloras. Pilocarpine Hydrochlorate. 

 C„ H,, N, O, H CI. (U. S. P.) 



Derivation. — The hydrochlorate of an alkaloid obtained 

 from pilocarpus, with alcohol and hydrochloric acid by dis- 

 tillation and evaporation. The residue is dissolved in a 

 slight excess of ammonia and chloroform, shaken with water, 

 and neutralized with hydrochloric acid. Crystals of the 

 hydrochlorate form on evaporation. The salt is purified by 

 recrystallization. 



PropeHies. — Small, white crystals, odorless and having 

 a faintly bitter taste ; deliquescent on exposure to damp air. 

 Very soluble in water and in alcohol ; almost insoluble in 

 ether or in chloroform. 



Dose. — H., sialogogue, gr.i.-ii. (.06-. 12); cathartic, gr.ii.-v. 

 (.12-. 3); C, cathartic, gr.v.-x. (.3-.6) ; H., diarphoretic. 

 gr.vi -xii. (.36-. 72), dangerous; Sh., gr.i. (.06); D., gi.^V"! 

 (.006-.02). 



