454 VEGETABLE DRUGS 



(h) Less Important Const{ttients.—{5) Kinic, or quinic 

 acid (C-HijOg), occurs in colorless prisms. Related to benzoic 

 acid and eliminated in the urine as hippuricaeid. Found in 

 coffee beans and other vegetables. 



The alkaloids in cinchona are naturally united with 

 kinic or kinovic acid, and salts of this combination are used 

 in medicine ; i.e., quinine kinate, which is soluble and may 

 be employed subcutaneously. 



(6) Kinovic, or quinovic acid (CjjH^gOg), a white, amor- 

 phous substance allied to kinovin. 



(7) Kinovin, or quinovin (CgpH^gO,), a glucoside readily 

 decomposed into glucose and kinovic acid. 



(8) Cincho-taunic acid, or kino-tannic and kinovi-tannic 

 acid (2-4 per cent.). The astringent principle of cinchona. 

 Distinguished from tannic acid in yielding green color with 

 ferric salts. 



(9) Cinchona red, the coloring matter of cinchona bark. 

 Nearly insoluble in water. 



(10) A volatile oil existing in minute amount. 



(11) Starch, gum, resin and salts common to other 

 vegetable matters. 



Incompatihility. — Cinchona is incompatible with lime 

 water, ammonia, metallic salts or gelatin. 



Dose.~R., 3 ii.-iv. (8.-15.); C, 3 i -ii. (30.-60.); Sh. &Sw., 

 3 i.-iv. (4.-15.) ; D. & C, gr.x.- 3 i. (.6-4.). 



PREPARATIONS. ' 



Extractum Cinchonce Fluidum. Fluid Extract of Cinchona. 

 (U. S. & B. P.) 



Made by maceration and percolation with glycerin, alcohol and 

 water ; evaporation of the last portion of the percolate, and addition of 

 the residue to first portion, with enough water and alcohol to make 

 1 Cc. = 1 Gm. of crude drug. (U. S. P.) 



Dose —Same as cinchona. 



Extractum Cinchonce. Extract of Cinchona. (U. S. P.) 

 Made by maceration and percolation with alcohol and water ; dis- 

 tillation of alcohol and evaporation to pilular consistence. 

 Dose.— H., 3 i.-ii. (4.-8.) ; D., gr.v.-xxx. (.3-2.). 



