HYDRASTININE HYDROCHLORATE 535 



.— H. & C, 3 ii.- 1 i. (8.-30.); Sh. & Sw., 3 i.-ii. (4.-8.); D., nv.- 3 i. 

 (.3-4.). 



Tinctura Hydrastis. Tincture of Hydrastis. (U. S. P.) 



Made by maceration and percolation of Hydrastis, 200 ; with diluted 

 alcohol, to 1000. 



Dose.—K., § i.-ii. (30.-60.) ; D., 3 ss.-ii. (2.-8.). 



Olyceritum Hydrastis. Glycerite of Hydrastis. (U. S. P.) 

 Made by maceration and percolation of hydrastis. 1000 ; add water 

 to the percolate and evaporate. Add water to the residue, set aside 24 

 hours and filter ; add enough water to the filtrate to make 500 ; then add 

 glycerin, 500. 



Dose. — Same as fluid extract. 



Hydrastinin^ Hydraschloras. Hjdiastinine Hydro- 

 chlorate. C,,H,,NO,H CI. (U. S. P.) 



The hydrochlorate of an artificial alkaloid derived from 

 hydrastine by the action of oxidizing agents. 



Properties. — Light, yellow, amorphous granules, or a 

 pale yellow crystalline powder ; odorless, and having a bitter, 

 saline taste ; deliquescent on exposure to damp air. Soluble 

 in 0.3 part of water, and in 3 parts of alcohol. 



i>ose.— H., gr.i.-ii. (.06-.12); D., gr.-jVi (.005-.01). 



Hydrastin. (Non-official). 



The commercial name for a mixture of variable com- 

 position, consisting chiefly of berberine, together with 

 hydrastine, and a resin. A greenish-yellow powder, having 

 a bitter taste. Wrongly termed hydrastine. 



Dose.—R., gr.xv.-xxx. (1.-2.); D., gr.iii.-v. (.18-.3). 



Actions. — Hydrastis and its alkaloids, berberine and 

 hydrastine, act as simple bitters and stomachics, in small 

 doses, by improving the appetite and stimulating the secre- 

 tion, motion and vascularity of the stomach. Hydrastis 

 causes contraction of the non- pregnant uterus, and may 

 induce abortion in pregnant animals. It also increases the 

 flow of bile and urine. The drug is a mild anti-periodic, but 



