FRANGULA 547 



Description. — In quills or curved pieces about 3 to 10 

 Cm. long and about 2 Mm. thick ; outer surface brownish- 

 gray and whitish ; the young bark having numerous rather 

 broad, pale-colored warts ; inner surface yellowish to light 

 brownish, becoming dark brown by age; smooth or finely 

 striate ; fracture short, yellowish ; in the inner layer of thick 

 bark somewhat fibrous ; inodorous ; taste bitter. 



Constituents. — 1, three resins ; 2, a neutral body ; 3, a 

 volatile oil ; 4, malic and tannic acids. 



Dose. — D., gr.v.-xxx. (.3-2.). 



PREPARATIONS. 



Extractum Bharnni Purshiance Fluidum. Fluid Extract of Rhamnus 



Purshiana. 



Made by maceration and percolation with diluted alcohol, and 

 evaporation, so that 1 Co. = 1 Gm. of the crude drug. . 



Dose.— D., TTiv.-xxx. (.3-2.). 



Extractum Cascarce SagradiB Liquidum. (B. P.) 

 Dose.—D., nv.-xxx. (.3-2.). 



Franoula. Frangula. (U. S. P,) 



Synonym. — Rhamni frangulae cortex, B.P.; buckthorn, 

 alder buckthorn, black alder, E.; bourdaine, bourgene, Fr.; 

 faulbaumrinde, G.; cortex frangulae, P.G. 



The bark of Rhamnus Frangula Linne (nat. ord. Rham- 

 nese), collected at least one year before being used. 



Habitat. — Europe and northern Asia. 



Description. — Quilled, about 1 Mm. thick ; outer surface 

 grayish-brown, or blackish-brown, with numerous small, 

 whitish, transversely-elongated lenticles ; inner surface 

 smooth, pale brownish-yellow; fracture in the outer layer 

 short, of a purplish tint ; in the inner layer fibrous and pale 

 yellow ; when masticated, coloring the saliva yellow ; nearly 

 inodorous ; taste sweetish and bitter. 



Constituents.— 1, a glucoside, frangulin (CjoHooOio), con- 

 verted in time into (2) emodin (C15H10O5), a glucoside, to 

 which the drug owes its purgative action. Frangulin yields 



k 



