POMEGRANATE 593 



Dose. —Small dogs, 3 ss.-i. (2.-4.) ; large dogs, 3 ii.-iv. 

 (8.-15.). 



PREPARATION. 



Extractum Cusso Fluidum. Fluid Extract of Kousso. (U. S. P.) 



Synonym. — Extractum brayerae fluidum. 



Made by maceration and percolation of kousso with alcohol, and 

 evaporation, so that 1 Cc. = 1 Gm. of the crude drug. 

 Dose. — Same as kousso. 



Action and Uses. — Kousso is an effective tseniacide in 

 dogs and cats. Large doses cause nausea, colicky pains and 

 some catharsis. Kousso is administered in milk, or as an 

 infusion flavored with peppermint ; also in the form of the 

 fluid extract, or glucoside in capsules, to the fasting animal. 

 It should be repeated 3 times, at hour intervals, and followed 

 by a small dose of castor oil if the bowels are not sufficiently 

 relaxed. There is little danger of poisoning even by great 

 quantities of the drug. 



Granatum. Pomegranate. 



Synonym. — Granati radicis cortex, B.P. ; ecorce de la 

 racine de grenadier (de balaustier), Fr.; granat-wurzelrinde, 

 G.; cortex radicis granati, P.G. 



The bark of the stem and root of Punica Granatum 

 Linne (nat. ord. Lythrariese). 



Habitat. — India and S. W. Asia. Also cultivated and 

 naturalized in sub-tropical countries. 



Description. — In thin quills or fragments, from 5 to 10 

 Cm. long, and from 1 to 3 Mm. thick ; outer surface yellowish- 

 gray, somewhat warty, or longitudinally and reticulately 

 rigid; the stem-bark often partly covered with blackish 

 lichens; the thicker pieces of the root-bark more or less 

 scaly externally ; inner surface smooth, finely-striate ; 

 grayish-yellow ; indistinctly radiate ; inodorous ; taste astrin- 

 gently, very slightly bitter. 



Constituents. — The active principle is (1) pelletierine 

 (CgHigNO), J per cent., a colorless, oil}^ aromatic alkaloid, 



