FURTHER DEVELOPMENT OF KNOWLEDGE 197 



alexic properties on preservation at room temperature within a few 

 days, and more slowly but no less regularly in the ice chest. This 

 anti-alexin is destroyed on heating to 56 C., and may be precipitated 

 out with the globulins of the serum. There appeared in these studies 

 no particular association between the anti-alexic property and ne- 

 phritis. 



The action of alexin upon sensitized cells may be prevented, also, 

 by physical or chemical conditions without actual fixation or binding 

 of the alexin. We refer to the effects of the addition of salts, prob- 

 lems which have been considered above. 



