566 



INDEX 



Agglutinins, heating of, ef- 

 fects of, 226 

 explanation of, 236 

 "immune," 234 

 in hemolytic serum, 93 

 nature of, 224 

 normal, 91, 233 



explanation of, 234 

 qualitatively identical 

 with "immune" 

 agglutinins, 234 

 production of, 129 

 Agglutinogen, 223 



effects of heating on, 



226 



localization of, in cell 



body proper, 225 



in ectoplasmic layer 



of cells, 224 

 in flagellar substance, 



224, 225 

 nature of, 224 

 Agglutinoids, 235 

 Aggressins, 326 

 action of, 21 

 obtaining of, 21 

 secretion of. by bacteria 

 in body, and vir- 

 ulence, 20-22 

 Albuminolysins, 193, 211, 



401 

 Alexin, 137 



a combination of soaps 



and proteins. 175 



absence of, from aqueous 



humor of the eye, 



170 



analogy between fer- 

 ments or enzymes 

 and, 176 

 bactericidal powers of, 



137 / 



definition of, 80 ^ 

 dependence of, on con- 

 centration, 176 

 extraction of, from leu- 

 kocytes and lym- 

 phatic organs, 

 304 et scq. 

 filtration of, 177 

 in hemolysis. 144 

 inactivation of, bv salt, 



178 



by salt-removal, 178 

 by shaking, 185 

 reversibility of. 184 

 Gramenitski's ex- 

 periments on, 184, 

 185 



increase of, on clot, 172 



influence of salts on 



action of, 177, 



178 



leukocytic origin of, 168, 



169 et seq. 

 multiplicity of, 154 et 



sea. 

 Borders views on. 



156 

 Ehrlich's views on. 



155 



nature of, 137. ir,4 

 chemical, 174. 175 

 physical, 177 

 presence of. in blood 



plasma, 170-1TL' 

 in blood stream, 170- 



172 



in normal blood, Gen- 

 gou's view of. 

 303, 304 



MetchnikofTs view 

 of, 302 



Alexin, presence of. in nor- 

 mal blood, other 

 experimenters on, 

 303 

 production of. in liver, 



173 



in thyroid gland, 172 

 varieties of : 



macrocytase, 169 

 microcytase, 169 

 Alexin fixation, 186 

 albuminolysin in, 193 

 identity of, with pre- 



cipitins, 193 

 writer's opinion on. 



193, 194 



Bordet and Gengou's ex- 

 periment on, 186. 

 187 



Bordet-Gengou phenome- 

 non in, 188 ct 

 stq. 



Gay's experiments sup- 

 porting, 190 

 in diagnosis of infec- 

 t i o u s diseases. 

 188 



in diagnosis of syph- 

 ilis. 188 



Moreschi's e x p e r i - 

 ments supporting. 

 189 

 Bordetscher Antikorper 



in, 194, 195 



by immune animal sera 

 with their specific 

 antigens. 189 

 by protein and antipro- 

 toin sensitizers, 

 188 



distinguished from com- 

 plement devia- 

 tion, 186 

 during hemolysis, nature 



of, 176 



Khrlich's (schematic) 

 conception of. 187 

 experiments of, on syph- 

 ilitic monkeys, 

 198. 199 



forensic tests in. 211 

 in ana phyla xis. 392 

 in determination of na- 

 ture of unknown 

 protein. 211 

 delicacy of. 212. 213 

 technique of. 212 

 in diagnosis of glanders. 



216 



in diagnosis of gonor- 

 rheal infections. 

 216 



in diagnosis of malig- 

 nant neoplasms. 

 213 

 von Dungern's method 



of. 214 

 antigen production 



for. 214 

 results of. 215 

 technique of, 214 et 



seq. 



in diagnosis of syphilis 

 in human beings, 

 199 



in diagnosis' of tubercu- 

 losis, 217 

 in Wassermann reaction, 



198 



nature of, 192 et seq. 

 non-specific. 195 



by heated normal 

 serum, 196 



Alexin fixation, non-spe- 

 cific, by lipoidal 

 substances in tis- 

 sues, 195 

 by preserved normal 



serum, 196, 197 

 by protein emulsion 

 and other ex- 

 tracts, 196 



by unsensitized bac- 

 teria, 195 

 of specific precipitates, 



190 et scq. 



albuminolysin identi- 

 cal with. 193 

 writer's opinion on, 



193, 194 

 Gay on, 190 

 Pfeiffer and Fried - 



berger on, 190 

 Sachs on, 191 

 writer on. 193, 194 

 practical applications of, 



198 

 precipitin reaction and, 



190, 192 

 Dean on, 194 

 Gengou on. 192 

 Neufeld and Ilaendel 



on, 194 



writer on. 193, 194 

 specific antiprotein sen- 



sitizers in. 192 

 with syphilitic serum in 

 antigens from 

 normal organs, 

 200 



Alexin splitting. 178 

 Brand on. 179 

 by method of Ferrata, 



178. 179 

 by method of Liefmann, 



184 

 by method of Sachs and 



Altmann, 184 

 effect of acid reaction on 

 fractious of, 181 

 end-piece in, 179 et 



seq. 

 mid-piece in, 179 et 



scq. 



heat sensitiveness of 

 fractions of, 180 

 interchange of fractions 

 of. in different 

 animals, 182 

 is it the inactivation 

 of the mid-piece 'i 

 183 



mid-piece only bound in 

 Wassermann reac- 

 tion. 181 



physical occurrence of 

 fractions of, in 

 blood. 181 

 presensitizetl cell in, 



180 

 properties of fractions 



of, 179 



quantitative relations 

 between fractions 

 of, 1S2, 183 

 Alexocytes. 168 

 Alkali-albuminate precipi- 

 tin, 260 



"Alkalinity theory" of 

 immunity, 83, 84 

 Amanita phalloides, spe- 

 c i f i c antitoxin 

 from. 96 

 Amboceptor, 149 



Bordet's definition o f, 

 159 



