INDEX 



567 



Amboceptor, complement- 

 ophile groups or 

 polyceptors o f 

 (Ehrlich), 149, 

 156 



cytophile group of, 149, 

 152, 153 



multiplicity of, 150, 151, 



154 



Ehrlich and Morgen- 

 roth on, 150, 151 



quantitative determina- 

 tion of, in im- 

 mune serum, 160, 

 161 



specificity of, 150 

 Amboceptor and comple- 

 ment, Ehrlich and 

 Sachs's views on 

 union of, 164. 165 



Noguchi's measurement 

 of quantitative 

 relations of, 164 



quantitative ratio be- 

 tween, 163. 164 

 Amebse, artificial, 294 

 Aiiaphylactic antibody, re- 

 lation of. to other 

 antibodies, 401 

 Anaphylactic intoxication, 

 peptone poisoning 

 and, 405 



Anaphylactic shock, 363 et 

 seq. See also Ana- 

 phylaxis, clinical 

 manifestation of 



effect of atropin and 

 other drugs on, 

 379 



histamin as cause of, 406 

 Anaphylactin. 385 

 Anaphylatoxin, 22, 394, 

 415 



action of alexin in. 425 

 with normal or in- 

 activated immune 

 serum, 425, 426 

 with salt solution, 426 



inhibition of. by too 

 vigorous and pro- 

 longed reaction. 

 419 



source of, 427 

 Anaphylaxis, 358 



alexin fixation in. 392 



analogy of immediate re- 

 action in serum 

 sickness to, 429 



analogy of serum sick- 

 ness to, 430 



analogy of tuberculin re- 

 action to, 444 



anaphylactic poisoning, 

 nature of, 404 et 

 seq. 



from precipitates. 394 

 proteid split products 

 of Vaughan and 

 Wheeler in, 405 

 symptoms of, similar 

 to peptone poi- 

 soning, 406 



Anderson and Schultz's 

 work on. 365 



anti-anaphylactic state 

 in. See Antiana- 

 phylaxis 



antigen in, intervals be- 

 tween administra- 

 tions of, 376 

 identity of sensitizing 

 and toxic sub- 

 stances of, 387 



Anaphylaxis, antigen i n, 

 identity of sensi- 

 tizing and toxic 

 substances of, 

 Doerr and liuss's 

 work on, 387 

 Wells' work on, 387 

 nature of, 370 

 path of introduction 



of, 374 



intracerebrally, 374 

 i n t r a-intestinally, 



375 



by feeding, 375 

 by rectum, 375 

 into large intes- 

 tine, 375 



intravenously, 374 

 subcutaneously, 374 

 quantity of, adminis- 

 tered, 376 et seq. 

 specificity of. 371 

 degree of, 372 

 organ, 373 



a u tosensitization 

 in, 373 

 species, 372 

 two separate sub- 



xtances in, 386 

 Doerr and Russ's 

 experiments on, 

 387, 389 



Gay and Adler's ex- 

 periments in. 3S6 

 Pick and Yamanou- 

 chi's experiments 

 in. 387 



Arthus' work on, 361 

 asthma and. 436 

 Auer and Lewis's work 



on. 364 

 autosensitization in, 373, 



439 



Besredka and Stein- 

 hardt's work on, 

 374 ct seq. 



Besredka's theory of, 386 

 Besredka's work on, 375 



ct seq. 



Biedl and Kraus's work 



on. 365. 368, 3(59 



Bogomolez's work on, 



371 



Calvary's work on, 369 

 cell participation in, 390, 



399 et seq. 

 clinical manifestations 



of, 363 

 in dogs, 368 



fall in blood pres- 

 sure in, 368 

 fall of temperature 



in, 369 

 increase of lymph 



flow in. 369 

 intestinal reaction 



in, 370 



lowered coagulabili- 

 ty of blood in. 36!) 

 in guinea pig, 363 

 alexin reduction in. 



367 



circulation symp- 

 toms in. 366 

 effect of atropin 

 and other drugs 

 on, 365 

 fall of temperature 



in, 366 



fever in, 366, 367 

 lowered coagulabil- 

 ity of blood in, 

 367 



Anaphylaxis, clinical mani- 

 festations of, in 

 guinea pig, pulmo- 

 nary emphysema 

 in, 364 



respiratory symp- 

 toms in, 364, 365 

 susceptibility o f 

 various breeds in, 

 368 



temporary diminu- 

 tion of polynu- 

 clear leukocytes 

 in, 367 

 in rabbits, 368 



clinical significance of, 

 428 



dependence of, on pre- 

 ceding inocula- 

 tion, 360 



diagnostic uses of, 446 



diminution of alexin af- 

 ter anaphylactic 

 shock in, 392 

 significance of, 392 



early work on, 359 



Flexner's work on, 359 



Friedberger's work on, 

 366 



Friedemann's e x p e r i- 

 ments in, in vitro. 

 393 



fundamental principles 

 of, 358 



Gay and Southard's ar- 

 guments against 

 antigen - antibody 

 reaction theory 

 of. 385 



Gay and Southard's the- 

 ory of, 386 



Gay and Southard's work 

 on, 364 



hay fever and, 436 



in serum therapy. See 

 Serum sickness 



in sudden attacks of ca- 

 tarrhal nasophar- 

 yngitis and con- 

 junctivitis, 437 



in vaccine therapy, 434 



incubation time in, 360, 

 376 



Jobling and Petersen's 

 work on, 396 



Lesne" and Dreyfus' 

 work on, 375, 376 



Magendie on, 359 



Manwaring's work on, 

 370 



mechanism of anti-ana- 

 phylaxis in, 402 

 et seq. 



desensitization in, 403 

 specificity in, 404 

 tolerance to anaphy- 

 lactic poison in, 

 403 



Nicolle's theory of, 391 



organ specificity in, 

 438 



Otto's work on, 361 



Pearce and Eisenbrey's 

 work on, 368, 369 



Pfeiffer's work on, 366 



phenomena related to, 



406 



toxic action of nor- 

 mal sera, 406 

 toxin hypersusceptibil- 

 ity, 409 



Pick and Yamanouchi's 

 work on, 371 



