574 



INDEX 



Haffkine's method in active 

 prophylactic im- 

 munization 

 against cholera, 

 488 



Half parasites, 11 

 Haptines, 129 



of the second order, 235 

 of the third order, 150 

 varieties of, 129 

 Haptophore group in toxin, 



110 



action of, 110 

 Haptophore groups in 



hemolysis, 142 

 Hay fever, anaphylaxis 



and. 436 



Dunbar's study of, 43G 

 reaction in, 436 



anaphylactic nature 



of, 437 



toxic nature of. 437 

 treatment of, 437 

 Heat alkali-precipitin. 259 

 Heat-precipitins. 259 

 Hemagglutination, agglu- 

 tination of bac- 

 teria by serum 

 analogous to, 23(5, 

 237 



Hemoglobinuria, paroxys- 

 mal, 147 



autohemolysins in, 147 

 hemolysis in, 147 

 Hemolysinogens, human. 



148 



nature of, 148 

 Ilemolysins, anti-isolysins 



in, 147 



autolysins in, 146, 147 

 isohemolysins in, 146 

 specific, definition of. 92 

 specific inciting of, in 



animal. 91 



Hemolysis, alexin or com- 

 plement in, 144 

 amboceptor in. action 



of. 149 et xeq. 

 anti-amboceptor in, 152, 



153 



anti-cytophile interpre- 

 tation of anti- 

 sensitization in 

 (of Ehrlich and 

 Morgenroth). 153 

 controversy on. 153 

 antisensitizer in, 152, 



153 



anti-isolysins in. 147 

 experiments of Liefmann 

 and Colin on. 145 

 in immune serum. 141 

 analogy of. to bacteri- 

 olysis. 142 



Bordet's work on. 141 

 Ehrlich and Morgen- 

 roth on mechan- 

 ism of, 142 

 haptophore groups in, 



142 



relation of antigen, 

 amboceptor and 

 complement i n, 

 143-145 



multiplicity of ambocep- 

 tor in, 150. 151, 

 154 



recapitulation of views 

 of Ehrlich and 

 Morgenroth on, 

 152 



Hemolytic properties of 

 normal serum, 91 



Hemolytic reactions, com- 

 plement deviation 

 in, 163 



Hemolytic serum, agglu- 



tinins in, 93 



Ehrlich and Morgen- 

 roth's conception 

 of neutralization 

 of, by antilysin 

 or anti-ambocep- 

 tor reacting with 

 cytophile group, 

 153 

 precipitins in, 94 



Hemolytic substances, ori- 

 gin of, from leu- 

 kocytes, 169 et 

 seq. 



Hepatotoxin, 92 



Hiss, investigations of. on 

 therapeutic use of 

 leukocyt e ex- 

 tracts. 308, 309 



Hiss and Zinsser's work on 

 injection of non- 

 specific substances 

 in infectious dis- 

 eases. 521 



Hog cholera, immunization 

 *v i t h bacterial 

 products in, 72 



Ilogyes method of treat- 

 ment in rabies, 

 494 



Holobut's work on bac- 

 terial anaphy- 

 laxis, 413 



Hopkins' method of stand- 

 ardization of vac- 

 cines, 353 



"Horror autotoxicus," 147 



Human isolysins. See Iso- 

 lysins, human 



Humoral theory of immu- 

 nity, 136 



Hydrophobia, active .pro- 

 phylactic immu- 

 nization against, 

 492. See also un- 

 der Rabies 



Hyperleukocytosis, specific. 

 309 



Hypersusceptibility. See 



Anaphylaxis 



toxin, and anaphylaxis, 

 409 



"Ideal fall." in syphilis, 



503 

 Immune bodies, structure 



of. 127 

 Immune serum. See also 



Serum, immune 

 agglutination in. 141 

 bacteriolytic power of 



transferable. 137 

 bacteriolytic properties 

 of, Bordet's find- 

 ings in. 140, 141 

 direct neutralization of 

 toxin - antitoxin 

 reaction, the pro- 

 tective power of, 

 124 

 hemolysis in. 141 



alexin or complement 



in. 144 



analogy of. to bac- 

 teriolysis, 142 

 Bordet's work on. 141 

 Ehrlich and Morgen- 

 roth on mechan- 

 ism of, 142 



Immune scrum, hemolysis 

 i n . haptophore 

 groups in, 142 

 relation of antigen, 

 amboceptor and 

 complement i n, 

 143-145 



work of Ehrlich and 

 Morgenroth o u, 

 143-144 

 work of Liefmann and 



Cohn on, 145 

 phagocytosis in, 90 

 specific, agglutination of 



bacteria in. 89 

 precipitin formation 



in, 90 



Immune isolysins, 148 

 Immunitats Einheit, 107 

 Immunity, 49 

 acquired, 60 

 artificially, 63 

 definition of, 63 

 history of, 61 

 increased phagocytosis 



and. 299 



active, relation of pha- 

 gocytosis to. 32!) 

 cellular theory of, 130 

 definition of, 3 

 diphtheria, determina- 

 tion of, wit h 

 diphtheria toxin, 

 464 



"high tide" of, 340 

 humoral theory of, 136 

 lasting, diseases in 

 which one attack 

 conveys, 60 



diseases in which one 

 attack does not 

 convey, 61 



local, in organs directly 

 in contact with 

 antigens. 102 

 in skin infections, 103 

 natural, 49 



cellular theory of. 80 

 definition of. 50, 62 

 humoral theory of, 



80 



inflammation in, 78 

 mechanism of, 78 

 theories concerning, 



78-82 



bacterial destruc- 

 tion by phago- 

 cytic cells, 78 

 bacterial growth 

 in cell - free 

 blood serum, 81 

 bactericidal pow- 

 er of blood in 

 natural immu- 

 nity, 80 



bactericidal pow- 

 er of normal 

 blood in nat- 

 ural immunity. 

 79 



bactericidal prop- 

 erties of extra- 

 vascular plas- 

 ma or serum, 

 81 



inhibition of bac- 

 terial growth 

 by c e 1 1 - f r e e 

 blood plasma, 

 79 



intracellular de- 

 struction o f 

 bacteria, 78 



