INDEX OF SUBJECTS 



529 



Amboceptor and comple- 

 ment, Ehrlich and 

 Sachs's views on 

 union of, 164, 165 

 Noguchi's measurement 

 of quantitative 

 relations of, 164 

 quantitative ratio be- 

 tween, 163, 164 

 Amebse, artificial, 294 

 Anaphylactic antibody, re- 

 lation of, to other 

 antibodies, 400 

 Anaphylactic intoxication, 

 peptone poisoning 

 and, 404 



Anaphylactic shock, 363 et 

 seq. See also 

 Anaphylaxis, clin- 

 ical manifestation 

 of 



effect of atropin and 

 other drugs on, 

 379 



Anaphylactin, 386 

 Anaphylatoxin, 22, 396, 



413 



action of alexin in, 422 

 with normal or in- 

 activated immune 

 serum, 422, 423 

 with salt solution, 424 

 inhibition of, by too 

 vigorous and pro- 

 longed reaction, 

 417 



source of, 424 

 Anaphylaxis, 358 



alexin fixation in, 394 

 analogy of immediate re- 

 action in serum 

 sickness to, 427 

 analogy of serum sick- 

 ness to, 428 



analogy of tuberculin re- 

 action to, 442 

 anaphylactic poisoning, 

 nature of, 403 et 

 seq. 



from precipitates, 396 

 proteid split products 

 of Vaughan and 

 Wheeler in, 403 

 symptoms of, similar 

 to peptone poi- 

 soning, 404 

 Anderson and Schultz's 



work on, 365 

 anti-anaphylactic state 

 in. See Antiana- 

 phylaxis 



antigen in, intervals be- 

 tween administra- 

 tions of, 376 

 identity of sensitizing 

 and toxic sub- 

 stances of, 389 

 Doerr and Russ's 



work on, 389 

 Wells' work on, 389 

 nature of, 370 

 path of introduction 



of. 373 



intracerebrally, 373 

 intravenously, 374 

 i n t r a-intestinally, 



374 



by feeding, 374 

 by rectum. 375 

 into large intes- 

 tine, 375 



subcutaneously, 374 

 quantity of, adminis- 

 tered, 376 et seq. 



Anaphylaxis, antigen in, 

 specificity of, 371 

 degree of. 371 

 organ, 372 



a u t o s e n sitiza- 

 tion in, 373 

 species, 372 

 two separate sub- 

 stances in, 388 

 Doerr and Russ's 

 experiments on, 

 388, 389 



Gay and Adler's ex- 

 periments in, 388 

 Pick and Yamanou- 

 chi's experiments 

 in. 388 



Arthus' work on, 361 

 asthma and. 434 

 Auer and Lewis's work 



on, 364 

 autosensitization in, 373, 



437 



Besredka and Stein- 

 hardt's work on, 

 374 et seq. 



Besredka's theory of, 387 

 Besredka's work on, 375 



et seq. 



Biedl and Kraus's work 



on, 365, 368, 369 



Bogomolez's work on, 



371 



Calvary's work on. 369 

 cell participation in, 390, 



397 et seq. 

 clinical manifestations 



of, 363 

 in dogs, 368 



fall in blood pres- 

 sure in, 368 

 fall of temperature 



in, 369 

 increase of lymph 



flow in. 369 

 intestinal reaction 



in, 370 



lowered coagulabil- 

 ity of blood in, 

 369 



in guinea pig, 363 

 alexin reduction in, 



367 



circulation symp- 

 toms in, 366 

 effect of atropin, 

 and other drugs 

 on, 365 

 fall of temperature 



in, 366 



fever in, 366, 367 

 lowered coagulabil- 

 ity of blood in, 

 367 



pulmonary emphy- 

 sema in, 364 

 respiratory symp- 

 toms in. 364, 365 

 susceptibility of vari- 

 ous breeds in, 368 

 temporary diminu- 

 tion of polynu- 

 clear leukocytes 

 in, 367 



in rabbits, 368 

 clinical significance of, 



426 



dependence of, on pre- 

 ceding inocula- 

 tion, 360 



diagnostic uses of, 444 

 diminution of alexin af- 

 ter anaphylactic 

 shock in, 394 



Anaphylaxis, diminution 

 of alexin after 

 anaph y 1 a c t i c 

 shock in, signifi- 

 cance of, 395 

 early work on, 359 

 Flexner's work on, 359 

 Friedberger's work on, 



366 



Friedemann's experi- 

 ments in, in vitro. 

 395 

 fundamental principles 



of, 358 



Gay and Southard's ar- 

 guments against 

 antigen - antibody 

 reaction theory 

 of, 387 



Gay and Southard's the- 

 ory of, 386 

 Gay and Southard's 



work on, 364 

 hay fever and, 434 

 in serum therapy. See 



Serum sickness 

 in sudden attacks of ca- 

 tarrhal nasophar- 

 yngitis and con- 

 junctivitis, 435 

 in vaccine therapy, 432 

 incubation time in, 360, 



376 



Lesne" and Dreyfus' 

 work on, 375, 376 

 Magendie on, 359 

 Manwaring's work on, 370 

 mechanism of anti-ana- 

 phylaxis in, 401 

 et seq. 



desensitization in, 401 

 specificity in, 403 

 tolerance to anaphy- 

 lactic poison in, 

 402 



Nicolle's theory of, 394 

 organ specificity in, 436 

 Otto's work on, 361 % 

 Pearce and Eisenbrey's 

 work on, 368, 369 

 Pfeiffer's work on, 366 

 phenomena related to, 405 

 toxic action of nor- 

 mal sera, 405 

 toxin hypersusceptibil- 



ity, 407 

 Pick and Yamanouchi's 



work on, 371 

 quantitative methods ap- 

 plied to study of, 



Ranzi's work on, 367 



relation of alexin to, 394 



relation of antibodies 

 of, to other anti- 

 bodies, 400 



Richet and HSricourt's 

 work on, 360 



Richet and Portier's 

 work on, 360 



Rosenau and Anderson's 

 work on, 362, 374 

 et seq. 



sessile receptors, theory 

 of. 390 



specificity of, 362, 363 



sympathetic ophthalmia 

 and, 437 



Theobald Smith phenom- 

 enon in, 361 



Theobald Smith's work 

 on. 363 



toxic action of normal 

 sera and, 405 



