538 



INDEX OF SUBJECTS 



Infection without infec- 

 tious disease, 6, 7 

 Infectious disease, defini- 

 tion of, 6, 8 



Inflammation, process of, 

 and phagocytosis, 

 280 et seq. 

 with pyogenic staphylo- 



cocci, 281 

 with tubercle bacilli, 



283 



Influenza, relative suscep- 

 tibility of man 

 and animals to, 

 53 



Inheritance, a factor in re- 

 sistance to infec- 

 tion, 56 



iso-agglutinins in blood 

 serum influenced 

 by, 58 

 Inhibition zones in colloid 



reactions, 162 

 in precipitation and ag- 

 glutination, 162 

 of sera in agglutination, 



236 



Intestinal tract, defence 

 of, in infection, 12 

 Iso-agglutinins, 237 

 grouping of, 237, 238 

 in blood serum, 58 

 value of presence of, 239 

 Isohemolysins, 146 

 Isolysins, human, 148 

 grouping of, 148 

 testing of, for trans- 

 fusion, 149 

 iso-agglutinins analogous 



to, 237 

 Isoprecipitins, 255 



Jacobsthal's ultramicro- 

 scopic method of 

 finding precipi- 

 tates in syphilitic 

 sera, 204 



Jenner, Edward, experi- 

 mentation of, for 

 i m muni zation 

 against small-pox, 

 62 



Jobling's work on serum 

 therapy in cere? 

 brospinal menin- 

 gitis, 470 



Jochmann's investigations 

 in serum therapy 

 of epidemic cere- 

 brospinal menin- 

 gitis, 469, 470 



Kolle's method of prophy- 

 lactic vaccination 

 in cholera, 486 



Kolle and Otto's investi- 

 gations in pro- 

 phylactic immuni- 

 zation against 

 plague. 487 



Kolle and Wassermann's 

 investigations in 

 serum therapy of 

 epidemic cerebro- 

 spinal meningitis, 

 469 



Kraus, Rudolf, discovery 

 of specific precip- 

 itins by, 248 



Kraus and Doerr's study 

 of bacterial ana- 

 phylaxis, 410, 411 



Kraus and Stenitzer's se- 

 rum in treatment 

 of typhoid fever, 



L+, definition of, 109 

 method of determination 

 of. 109 



Lo, definition of, 109 

 constancy of. 110 

 method of determination 

 of. 110 



Laking, erythrocyte, 91 



"Landsteiner phenomenon" 

 of autohemolysis 

 in hemoglobin- 

 uria, 147 



Leishmann's technique for 

 determination of 

 opsonic index. 329 



"Leistungskern," definition 

 of, 126 



Leprosy, relative suscepti- 

 bility of man and 

 animals to, 54 



Lesne" and Dreyfus' work 

 on anaphylaxis, 

 375, 376 



Leukine, 305 



Leukocyte extracts, thera- 

 peutic use of, 308 

 et seq. 



Leukocytes, alexin extrac- 

 tion from, 304 et 

 seq. 

 growth of bacteria in, 



298 

 in bacteriolysis, 140 



action of, 168 

 in leukocytosis, action 



of, 275, 276 

 in phagocytosis, 324 

 origin of bactericidal 

 and hemolytic 

 substances from, 

 168, 169 et seq. 

 phagocytic powers of, 



50 



proteolytic enzymes 

 from, in phagocy- 

 tosis, 306, 307 



Leucocytosis, 290 



bacteria decreasing, 290 

 bacteria increasing, 290 

 sources of leukocytes in, 

 290 



Leukoproteases, 306, 307 



Leukotoxin, 92 



Limes-necrosis (L-n), 461 



L i p o i d constituents of 

 cells, relation of, 

 to antigenic prop- 

 erties, 97 



Lister on phagocytic activ- 

 ities of blood in 

 natural immunity, 

 79 



Liver, production of alexin 

 in, 173 



Loeb's experiments with 

 eggs of Fundulus, 

 517 



Lubarsch on bactericidal 

 properties of ex- 

 travascular plas- 

 ma or serum in 

 immunity, 81 



Ludke's work on serum 

 therapy in ty- 

 phoid fever, 477 



Lustig's antiplague se- 

 rum, 480 



Lysins, production of, 130 



Macrocytase, 169, 301 



Magendie on anaphylaxis, 

 359 



Malta fever, relative sus- 

 ceptibility of man 

 and animals to, 53 



Manwaring's work on ana- 

 phylaxis, 370 



Markls serum in treat- 

 ment of plague, 

 479 



Marmorek's work on serum 

 therapy of strep- 

 tococcus infec- 

 tions. 472, 473 



Measles, relative suscepti- 

 bility of man and 

 animals to, 54 



Meat poisoning, 4, 31 



Meistagmin reaction, 496 

 Ascoli and Izar's experi- 

 ments in, 496, 497 

 value of, in diagnosis, 

 497 



Meningitis, epidemic cere- 

 brospinal, serum 

 therapy of, 469. 

 See also under 

 C e r e b r ospinal 

 meningitis, epi- 

 demic 



Metabolism, processes of, 

 compared with 

 those of antibody 

 formation, 125 



Metchnikoff and Besredka's 

 living sensitized 

 vaccines for pro- 

 phylactic typhoid 

 immunization. 484 



Metchnikoff on bacterial 

 growth in cell- 

 free blood serum, 

 81 



theory of, on bacterial 

 destruction by 

 phagocytic cells 

 in natural immu- 

 nity, 78 



Metchnikoff 's soured milk 

 therapy, 31 



Microcytase, 169, 301 



Minimum lethal dose, defi- 

 nition of, 108, 109 

 method of determination 

 . of, 109 



MLD, definition of, 108, 



109 



method of determination 

 of, 109 



Morgenroth's toxin - HC1 

 modification in 

 t o x i n-antitoxin 

 reaction, 106 



Mucous membranes, de- 

 fence of, in infec- 

 tion, 12, 13 



Mushroom, specific anti- 

 toxin from, 96 



Narcotics, reduction of 

 phagocytosis by, 

 299 



Natural immunity. See 

 Immunity, nat- 

 ural 



"Negative" phase in active 



immunization, 338 



second injection in, 338 



successive inoculations 



in, 338, 339 



"summation'' of, 338, 

 339 



