INDEX OF SUBJECTS 



545 



Tubercle bacilli, effect of 

 body temperature 

 on virulence of, 12 



Tuberculosis, avian type, 

 relative suscepti- 

 bility of animals 

 to, 52 



bovine type, relative sus- 

 ceptibility of man 

 and animals to, 52 

 human type, relative 

 susceptibility of 

 man and animals 

 to, 52 



meistagmin reaction in 

 diagnosis of, 497 

 of cold-blooded animals, 

 immunity of 

 warm-blooded ani- 

 mals to, 52 



opsonic index in, 341- 

 342, 343 



Tuberculin ophthalmoreac- 

 tion, anaphylactic 

 nature of, 440 



Tuberculin reaction, anal- 

 ogy of, to ana- 



phylaxis, 442 

 rlactic i 



anaphylactic nature of, 



438 



Bail's experiments with 

 passive sensitiza- 

 tion in, 443 

 diagnostic value of, 442 

 Koch's experiments in, 



439 

 nature of, 438 



Babes' interpretation 



of, 439 

 Koch's interpretation 



of, 439 



Wassermann and 

 Brucks' interpre- 

 tation of, 439 

 specific antibody forma- 

 tion in, 442 



Tuberculin skin reaction, 

 anaphylactic na- 

 ture of, 440 

 von Pirquet's interpreta- 

 tion of, 441 

 Tuberculins, 355 



Bouillon^ Filtre (Denys), 



357 

 New Tuberculin (TR 



and TO). 356 

 New Tuberculin Ba cil- 

 iary Emulsion, 

 357 

 Old Tuberculin (Koch), 



355 

 Sensitized Tuberculin, 



357 



Tumors, malignant, alexin 

 fixation in diag- 

 nosis of, 213 

 von Dungern's method 



of, 214 

 antigen production 



for, 214 

 results of, 215 

 technique of, 214 et 



seq. 

 organ-specific qualities 



in, 373 



Typhoid bacilli, attenua- 

 tion of virulence 

 of, 18 



Typhoid carriers, 3 

 Typhoid fever, adaptation 

 of bacteria in, 8 

 agglutination reaction 

 for diagnosis of, 

 219 



Typhoid fever, agglutina- 

 tion reaction for 

 diagnosis of mac- 

 roscopic method, 

 219 



microscopic method, 



220 



effect of path of intro- 

 duction of bac- 

 teria of, on infec- 

 tion, 14 

 meistagmin reaction in 



diagnosis of, 497 

 prophylactic immuniza- 

 tion against, ac- 

 tive, 482 



early experimentation 

 in, 482 



living sensitized vac- 

 cines used in, 484 



results of, in United 

 States Army, 483 



Russell's vaccines in, 

 483 



sensitized killed vac- 

 cines in, 484 

 relative susceptibility of 

 man and animals 

 to, 54 

 serum therapy in, 475 



Besredka's anti-endo- 

 toxic serum in, 476 



Chantemesse's early 

 experiments in, 

 475 



Garbat and Meyer's 

 work on. 477 



Kraus and Stenitzer's 

 serum in, 477 



Gottstein - M a t h e s' 

 work on, 477 



Liidke's work on, 477 



nature of reaction in, 



476 



Typhus fever, relative sus- 

 ceptibility of man 

 and animals to, 54 



Ultramicroscope, 503 



Vaccination, prophylactic, 

 in man, 481 



in anthrax, 64 



in cholera, 484. See also 

 under Cholera 



in plague, 486. See also 

 under Plague 



in rabies, 489. See also 

 under Rabies 



in small-pox, 488. See 

 also under Small- 

 pox 



history and general 

 principles of, 62 



in typhoid fever, 482. 

 See also under 

 Typhoid fever 

 Vaccine therapy. See also 

 Immunization, ac- 

 tive 



anaphylaxis in, 432 



as a therapeutic meas- 

 ure, action of, in 

 local infections, 

 346 



in generalized sys- 

 temic infections, 

 347 

 in successive local 



infections, 347 

 value of, in acute dis- 

 eases, 350 



Vaccine therapy, as a 

 therapeutic meas- 

 ure, value of, in 

 subacute or 

 chronic cases, 349 

 autoinoculations by mas- 

 sage or exercise 

 in, 340 

 "high tide" of immunity 



in, 340 



"negative" phase in, 338 

 second injection in, 



338 

 successive inoculations 



in, 338, 339 

 summation of, 338. 339 

 opsonic index in, 328 et 



seq. 



comparison between 



that in exudate of 



infected foci and 



blood serum, 340 



improvement and, 341 



in tuberculosis, 341- 



343 



Leishmann's technique 

 for determination 

 of, 329 



Simon, Lamar and 

 Bispham's tech- 

 nique for deter- 

 mination of, 332, 

 333 

 value of. 338 



in controlling thera- 

 peutic vaccina- 

 tions, 344 



in showing degree 

 and conditions in 

 which vaccination 

 is successful, 344, 

 345 



Wright's technique for 

 determination of, 

 330 et seq. 

 difficulties in, 332, 



333 



value of, 333 

 relation of phagocytosis 



to, 329 

 second positive phase in, 



339 

 "summation of positive 



phase" in. 339 

 tuberculins in, 355 

 value of, as prophylactic 

 measure, 345, 

 346 



as therapeutic meas- 

 ure, 346 



Vaccines, autogenous, 351 

 production of, 351 



with dead bacteria, 



351 

 with living bacteria, 



351 



sensitized, 355 

 standardization of, 352 

 Hopkins' method of, 



353 

 Wright's method of, 



352, 353 



Vaughan's work on ana- 

 phylaxis, 366.367 

 on bacterial anaphylaxis, 



412 



Vaughan and Wheeler, pro- 

 teid split prod- 

 ucts of, in ana- 

 phylactic poison, 

 403 



theory of, on mechanism 

 of anaphylaxis, 

 393 



