576 



INDEX 



Infection, effect of path of 

 introduction o f 

 bacteria on. 12-14 

 effect of quantity of 

 bacteria intro- 

 duced on, 14 

 entrance of bacteria in 

 body tissues in, 6 

 focus in, 7-9 

 from bacteria in blood 



stream, 24 

 generalized, 24 

 increased invasive pow- 

 ers of bacteria a 

 factor in, 56 

 incubation of bacteria 



in. 26 

 individual differences 



and. 50 



inheritance and resis- 

 tance to, 56 

 localized. 23 

 reaction in, 26 

 selective action of 



bacteria in, 25 

 through accidental 



conditions. 25 

 natural resistance 



against, 40 



of various diseases, rel- 

 ative susceptibil- 

 ity of man and 

 animals to. 52 

 protective action of 

 blood serum 

 against. 50 



protective action of leu- 

 kocytes against. 

 50 



protective action of tis- 

 sues against. 50 

 ptomains and. 2S 

 ptomains a s indirect 



cause of. 31 

 racial differences and. 



55 

 resistance of living cell 



to. 6 

 secondary abscesses in. 



25 



secondary modifying fac- 

 tors in. 2 



selective lodgment of 

 bacteria in body 

 and. 40 



similar, produced by dif- 

 ferent bacteria, 

 23 



species resistance to. 51 

 specificity of bacteria 



and. 22 



susceptibility to. racial 

 differences in, 55 

 relative, 51 



variation in, of differ- 

 ent strains of 

 same bacteria, 15, 

 16 



variation in degree of, 

 in bacteria suc- 

 cessively passed 

 through animals, 

 16, 17 



without infectious dis- 

 ease. 6, 7, 517 

 Infectious disease, defini- 

 tion of, 6, 8 



influence of injections of 

 non-specific sub- 

 stances upon, 520 

 Inflammation, process of, 

 and phagocvtosis, 

 280 et seq.' 



Inflammation with p y o - 

 genie staphylo- 

 cocci. 281 

 with tubercle bacilli, 



283 



Influenza, relative suscep- 

 tibility of man 

 and animals to, 

 53 



Inheritance, a factor in re- 

 sistance to infec- 

 tion, 56 



iso-agglutinins in blood 

 serum influenced 

 by, 58 

 Inhibition zones in colloid 



reactions, 162 

 in precipitation and ag- 

 glutination, 162 

 of sera in agglutination. 



236 



Intestinal tract, defence 

 of, in infection, 

 12 



Iso-agglutinins. 237 

 grouping of. 237. 238 

 in blood serum. 58 

 value of presence of, 230 

 Isohemolysins, 146 

 Isolysins, human, 148 

 grouping of. 148 

 testing of, for trans- 

 fusion. 140 

 iso-agglutinins analogous 



to. 237 

 Isoprecipitins, 255 



Jacobsthal's ultramicro* 

 scopic method of 

 finding precipi- 

 tates in syphilitic 

 sera, 204 



Jenner, Edward, experi- 

 mentation of, for 

 i m m u n i za tion 

 against small-pox, 

 62 



Jobling's work on serum 

 therapy in cere- 

 brospinal menin- 

 gitis. 472 



.Tobling and Petersen's 

 work on ana phy- 

 la xis. 396 



Jochmann's investigations 

 in serum therapy 

 of epidemic cere- 

 brospinal menin- 

 gitis, 471, 472 



Kolle's method of prophy- 

 lactic vaccination 

 in cholera, 489 



Kolle and Otto's investi- 

 gations in pro- 

 phylactic immuni- 

 zation against 

 plague, 489 



Kolle and Wassermann's 

 investigations in 

 serum therapy of 

 epidemic cerebro- 

 spinal meningitis, 

 471 



Kraus, Rudolf, discovery 

 of specific precip- 

 itins by, 248 



Kraus and Doerr's study 

 of bacterial ana- 

 phylaxis, 412, 413 



Kraus and Stenitzer's se- 

 rum in treatment 

 of typhoid fever, 

 479 



L+, definition of, 109 

 method of determination 



of. 109 



L , definition of, 109 

 constancy, 110 

 method of determination 



of. 110 



Laking, erythrocyte, 91 

 "Landsteiner phenomenon" 

 of autohemolysis 

 in hemoglobin- 

 uria, 147 



Leishmann's technique for 



determination of 



opsonic index. 320 



"Leistungskern," definition 



of, 126 



Leprosy, relative suscepti- 

 bility of man and 

 animals to, 54 

 Lesne and Dreyfus' work 

 on anaphylaxis, 

 375, 376 

 Leukine, 305 

 Leukocidins, 21 

 Leukocyte extracts, thera- 

 peutic use of, 308 

 et seq. 



Leukocytes, alexin extrac- 

 tion from, 304 et 

 seq. 

 growth of bacteria in, 



298 

 in bacteriolysis, 140 



action of, 168 

 in leukocytosis. action 



of, 275, 276 

 in phagocytosis, 324 

 origin of bactericidal 

 and hemolytic 

 substances from, 

 168, 160 et seq. 

 oxidase in, 527 

 phagocytic powers of, 50 

 proteolytic enzymes 

 from, in phagocy- 

 tosis. 306, 307, 

 525. 526 

 Leukocytosis. 200 



bacteria decreasing. 290 

 bacteria increasing. 290 

 sources of leukocytes in. 



200 



Leukoproteases. 306, 307 

 Leukotoxin. 92 

 Limes-necrosis (L-n). 463 

 L i p o i d constituents of 

 cells, relation of, 

 to antigenic prop- 

 erties, 97 



Lister on phagocytic activ- 

 ities of blood in 

 natural immunity, 

 79 

 Liver, production of alexin 



in, 173 



Loeb's experiments with 

 eggs of Fundulus, 

 561 



Lubarsch on bactericidal 

 properties of ex- 

 travascular plas- 

 ma or serum in 

 immunity, 81 



Liidke's work on serum 

 therapy in ty- 

 phoid fever, 479 



