162 PASTEUR AND HYDROPHOBIA m 



APPENDIX 



The period of two years and a half whicli has elapsed 

 since the preceding article was written has extended 

 our knowledge of the results of Pasteur's system of 

 inoculation, and has also given more definite shape to 

 the theories as to the modus oj^erandi of the protect- 

 ive virus. Up to the commencement of last summer 

 7000 persons had been inoculated at the Institut 

 Pasteur in Paris. The average mortality of these in- 

 dividuals was 1 per cent, or, in other words, there 

 were 70 deaths. If the mortality had been 15 per 

 cent — the percentage of deaths of persons bitten by 

 rabid dogs, as nearly as can be estimated, before 

 Pasteur's treatment was known — then there would 

 have been as nearly as possible 1000 deaths ; so that 

 we are justified in saying that Pasteur has already 

 saved in this one institute alone 900 lives. Even if 

 we make a reduction in the number of cases treated 

 by considering those only in which the dog which bit 

 was certified to be rabid by a veterinary surgeon, 

 or experimentally proved to be so by inoculations 

 made after its death with its spinal cord, .we have 

 still 4500 cases, with a mortality of 70 instead of a 

 mortality of 675. In various places in Eussia and 

 Italy, and in Turkey and Havana, Pasteur's system 

 has been introduced with the same satisfactory re- 



