Ill PASTEUE AND HYDROPHOBIA 163 



suits, viz. a reduction of the mortality of persons 

 bitten by rabid dogs from 15 per cent to 1 or 2 

 per cent. 



The number of inoculations with the preventive 

 virus and the strength of the virus used has been 

 gradually modified during the past two years, in 

 such a way as to render the later results better than 

 those at first obtained. In fact, the latest returns 

 show a reduction of the mortality to less than 

 1 per cent, and in some series to zero — as, for 

 instance, at Warsaw, where Dr. Bujarid inoculated 

 in 1887-88 no less than 370 persons, all bitten 

 by animals proved to be rabid ; of these persons 

 not one died. A similar result w^as obtained at 

 Palermo by Dr. A. Celli, who in 1887-88 inoculated 

 609 persons. 



The following fact is perhaps the most convincing 

 in regard to the efficacy of Pasteur's treatment. In 

 the year 1887 the official medical report shows that 

 350 people were bitten in Paris by animals suffering 

 from rabies. 306 of these persons were inoculated at 

 the Institut Pasteur ; of these 3 died. 44 of the 350 

 declined to be inoculated, and of these 7 died. We 

 have here the two groups — the inoculated and the 

 non-inoculated — drawn indifferently from the same 

 population, living under the same average conditions, 

 and subjected to treatment at the same time. The 

 results are precisely confirmatory of the conclusions 

 arrived at from the study of the larger series of figures 

 derived from less rigidly established data. The per- 

 centage of the deaths of those who refused to be in- 



