CONTENTS xi 



CHAPTER X 



PAGES 



THE INTERNAL SECRETION OF THE REPRODUCTIVE ORGANS . . 07 92 



A. The internal secretion of the testis .... 67 74 



Subcutaneous injections of extracts of testis ... 67 

 Poehl's " spermin " . . . . . .67 



Effects of castration . . . . . . .68 



Male sopranos ... ..... 68 



Effects of tying the vasa defereritia . . . .70 



Interstitial cells .... .... 70 



Transplantation of the testis . . . . .71 



Therapeutic uses of extracts of testis . . . . 74 



B. The Internal secretion of the prostate gland . . . 74 75 



Extirpation of the prostate . . . . . .74 



Administration of extracts of prostate . . . .75 



C. The internal secretion of the ovary and the corpus luteum . 75 89 



Structure of the ovary . . . . . .75 



Cyclical changes in the ovary and in the uterus ... 75 

 Extirpation of the ovaries before puberty. ... 76 



Extirpation after puberty . . . . . .76 



Effects of ovariotomy . . . . . . .77 



Ovarian transplantation . . . . . .78 



Classification of sex characters ..... 80 



Structure of the corpus luteum ... .81 



Mode of formation of the corpus luteum . . . .81 



Chemistry of the corpus luteum ..... 83 



Effects of corpus luteum extracts . .84 



Ovarian extracts ...... .85 



Changes in the uterine mucosa produced by the corpus 



luteum ..... 86 



Function of the corpus luteum ... .88 



Interstitial cells . . . . . . . .88 



" Femininity "....... 89 



U. Ovarian medication ....... 90 91 



E. Osteomalacia . . 92 



CHAPTER XI 



THE INTERNAL SECRETION or THE ADRENAL BODIES (THE CORTEX OF 



THE ADRENAL AND THE CHROMAPHIL TISSUES) . . . 93 249 



A. Introductory .... 



Early history of the subject. 



B. Comparative anatomy of the adrenal bodies . 



1. Introductory ... .... 



2. Invertebrata ' . 



3. Anamnia ..... 



Cyclostomata .... 



Elasmobranchii 



Teleostei . 



Ganoidei 



Dipnoi ... 



Amphibia. . .109 



Anura 



Urodela ll 



