122 THE DUCTLESS GLANDS 



will be seen that there is a very considerable and very char- 

 acteristic rise of the blood-pressure. 



The investigations of Stilling were confirmed and extended 

 by Kohn and Rose, who laid stress on the fact that the chroma- 

 phil cells are common and typical elements of the mammalian 

 sympathetic system. Kohn's view is that what is ordinarily 

 called the " cortex " of the adrenal is in reality the only part 

 which ought to be called adrenal at all, while the medulla is 

 simply the " paraganglion suprarenale," a group of what he 

 called " chromaffin " cells, which have become included in the 

 adrenal. This matter will be referred to again later on. 



Fio. 36. Dog, 8 kilogrammes. November 10, 1909. CHC1 3 , morphine, 

 atropine. Carotid blood -pressure. Time in seconds. At the point 

 signalled an extract from the chromaphil bodies of three dogs was injected 

 into the saphenous vein. 



Zuckerkandl in 1901 found in the retroperitoneal space at 

 the origin of the inferior mesenteric artery a pair of large 

 chromaphil bodies, which he called " Nebenkorper des 

 Sympathicus." These he found constantly in the embryo 

 and in the new-born human subject, and, as we have seen, 

 Biedl and Wiesel found that the bodies contained a pressor 

 substance. 



True accessory adrenals, containing both cortex and medulla, 

 like the main gland, are said to occur in the neighbourhood of 

 the abdominal sympathetic, and in the region of the body where 

 the cortical elements first arise. 





