THE ADRENAL BODIES 227 



augmentation of the heart is very manifest (47, 48, 49, and 

 others). 



The curve just described is, we believe, to be regarded as 

 the normal effect of stimulation of the peripheral end of the 

 splanchnic nerve in the dog, as well as in the cat and the rabbit, 

 when these animals are under the influence of ether alone, or 

 under morphine and curare in addition, although under the 

 influence of the latter drugs the " dip " is much less pronounced 

 and sometimes altogether abolished. 



Anrep, in discussing Elliott's results, says " Eliott investi- 

 gated the question in the cat, in which animal the ' step ' 

 becomes a distinct fall." As we have already stated, in our 

 experiments there was no essential difference in this respect 



FIG. 48. Dog, 10 K. Ether, vagi cut, both splanchnics cut in thorax, (a) 

 Stimulation of left splanchnic five minutes after injection of 2 cc. of 1 % 

 morphine sulphate. (6) Stimulation fifteen minutes later. (c) Stimu- 

 lation fifteen minutes still later. The effect of the morphine wears off and 

 the normal curve tends to appear again. 



between dogs and cats. The "step" referred to by Anrep 

 is therefore not what we have called the " hump," but some- 

 thing which occurs later and which we call the " dip . " We have 

 not been able to convince ourselves that the nature of the 

 normal curve is dependent on nervous or emotional conditions 

 either in dogs or in cats. 



According to Elliott the " dip " of the splanchnic curve 

 in cats does not occur if the adrenal bodies are excised or tied 

 off. Anrep reports that the " step " in dogs is in a similar 

 manner abolished by suppression of the adrenal bodies. Gley 

 and Quinquaud, on the contrary, believe that there is an impor- 

 tant difference in the results between dogs and cats . They state 

 that interference with the adrenal bodies does not affect the 



