viii. Contents 



PAGE 



THE SUPRARENAL SYSTEM 124 



The Interrenal and Adrenal Systems, Historical ... ... 124 



Comparative Morphology and Embryology 127 



Physiology of the Suprarenals ... ... ... ... ... 134 



Experimental Extirpation ... ... ... ... ... 134 



The Results of the Extirpation of the Cortical and 



Medullary Substances w. 146 



Experimental Extirpation with Fish 150 



Symptomatology of Suppression of the Suprarenal Function ... 153 



Suppression of the Suprarenal Function in Man ... ... 158 



The Symptomatology of Addison's Disease ... ... ... 163 



Suprarenal Substitution 165 



Organotherapy 165 



Transplantation of the Suprarenals ... ... ... ... ... 168 



The Activity of Suprarenal Extract 173 



Chemistry of the Specific Active Substance present in the Supra- 

 renals 177 



The Physiological Activity of Adrenalin 183 



The Physiological Effects of Adrenalin upon the Sympathetic 



System ... ... ... ... ... ... ... ... 196 



The Site of Action of Adrenalin ... ... ... ... ... 227 



The By-effects of Adrenalin 234 



Toxic Action 236 



Adrenalin as a Secretory Produce of the Adrenal System ... 246 



Experimental Suprarenal Stimulation, Experimental 



Hypersecretion ... ... ... ... ... ... 260 



Pathological Adrenalinaemia as Seen in Man ... ... 262 



The Function of the Adrenal System 264 



The Interrenal System 267 



Histology of the Suprarenal Cortex 270 



Chemistry of the Suprarenal exclusive of Adrenalin ... ... 274 



Theory of the Function of the Interrenal System ... ... 20,2 



The Suprarenal considered as an Entity ... ... ... ... 295 



Carotid Gland and Coccygeal Bodies ... ... ... ... 302 



HYPOPHYSIS CEREBRI (Cerebral Appendage, Pituitary Gland) 305 



Anatomy '. 306 



Histology 308 



History of Development 313 



Physiology of the Hypophysis 315 



Pituitary Extract ... 321 



The Physiological Activity of Pituitary Extract ... ... 323 



Experimental Stimulation of the Hypophysis ... ... 328 



Diseases of the Hypophysis in Man 330 



Theory of the Function of the Hypophysis 348 



THE PINEAL BODY (Glandulae pinealis, Epiphysis, Conarium) 350 



THE GENERATIVE GLANDS 355 



The Results of Castration 376 



The Sexually Undifferentiated Activity of the Hormone 



in the Generative Glands 382 



Extract of the Generative Glands 389 



The Internal Secretory Tissue Elements of the Generative 



Glands 391 



Internal Secretion of other parts of the Genital Apparatus ... 410 



THE INTERNAL SECRETION OF THE PANCREAS 412 



Metabolism in Pancreatic Diabetes ... ... ... ... ... 415 



Theory of Pancreatic Diabetes ... ... ... ... ... 420 



The Internal Secretory Tissue Elements of the Pancreas ... 432 



THE INTERNAL SECRETION OF THE GASTRIC AND INTESTINAL MUCOSA ... 438 



THE INTERNAL SECRETION OF THE KIDNEY 440 



LITERATURE 446 



List of Contractions used in the Literature References 446 



