5 88 



INTERNAL SECRETION 



Adrenalin action, experiments to de- 

 termine nature, 202 



neutralized by apocodein, 203 



- on heart of cold and warm 

 blooded animals compared, 202 



on lachrymal glands, 212 

 on lymphatics of peritoneum, 



213 



on metabolism, 214, 215 



on muscles, 228, 229 



on organs innervated by sym- 



pathetic system, 189 



on pancreas, 212 



on pigment cells and granules 

 of frog, 214 



- on pregnant uterus, altered by 

 ergot, 232 



on pupil, 230 



on respiration, 235 



on salivary glands, 211 



on submaxillary glands, 211 



on sweat-glands, 214 



on sympathetic and autonomous 



nervous system compared, 230, 

 231 



contrasted, 231 



on urinary bladder, 205 f 



on uterus, 206, 207 



as quantitative test, 207 



, therapeutic, 207 



, amount in suprarenal capsules, 



182, 248, 249 



, modification by path- 

 ological conditions, 249 

 , antagonism of cholin to, 276, 278 

 , by-effects of, 234-236 



causing abortion, 207 



mydriasis in Graves's disease, 



211 



, cells producing, 253 

 , chemical tests for, in liquids and 

 secretions, 180, 181 



, colorimetric methods, 

 181, 182 



contents in cats and rabbits 



compared, 251 



- of dog, 254 



of suprarenals in Addison's 



disease, 250 



, conversion of tyrosin into, 180 

 - , destruction of, factors in, 256, 257 



, diabetes, 220 



, disassimilatory hormone, 206 

 , disassociation of auricular and 



ventricular beats under, 203 

 , drugs antagonistic to, in action, 



200 

 , effects after thyroidectomy and \ 



thyroparathyroidectomy, 54, 55 

 , modified by previous adminis- 

 tration of curarin, 196, 197 



determined by Meyer's method, 

 1 99 



on arteries, 198 



on coronary vessels of heart, 



1 86 



Adrenalin, effects on heart, how and 

 when determined, 200 



on nerve-endings, 197, 198 



on pigment in Addison's disease, 

 165 



- on pulmonary circulation, 185 

 - vessels negative, 197 

 - on thyroid gland, 28 

 - , excretion of, 256 



of lymph from thoracic duct 



promoted by, 213 

 , formation of, relation to chemical 



processes of muscles, 296 

 , function of, 266 



, connected with sympathetic 



system, 266, 267 

 Adrenalin-glycosuria, 215, 259, 429 



accompanied by hyperglycaemia, 

 216 



- , effect of subcutaneous injection 



of chyle on, 431 

 , experimental, and puncture of 



fourth ventricle, 219 



- , inhibition of, 220, 221 



by fever, 221 (footnote) 



by hirudin, 221 



by lymphagpga, 221 



by pancreatic extract, 429^ 



by pilocarpin, 226 



, mechanism of, 217, 218 

 Adrenalin in blood, 250, 251 



, disappearance, 256-258 



, persisting after cessation of 

 specific action, 258 



, ultimate fate of, 255 



, see also Adrenalscmia 



- in collapse, 188, 189 



in heart failure, 188, 189 



- following diphtheria, 189 

 - , increases secretion of bile, 212 

 , inhibitory influence on activity of 



pancreas, 221, 226 



, injection of, contraction of blood- 

 vessels following, 196 



followed by glycosuria after 



parathyroidectomy, 68 

 . not followed by glycosuria in 



thyroidectomized animals, 68 

 , intravenous injection, antidote to- 

 poisoning by chloral, 201 

 causing dilatation of cerebral 

 vessels, 185 



in urine, method of testing for, 182 

 , isolation methods, 177, 178 



, matrix of, 180 



mydriasis, inhibition of, 220 



, neutralization of strychnine by, 



295 



, organic composition, 179, 180 

 , physiological activity, 183 



effects on sympathetic system, 



196 



- poisoning, symptoms of various 



animals dying from, 238 

 > portion of blood-vessels acted on 



by, 187 

 , precursors of, 296, 297 



