590 



INTERNAL SECRETION 



Athyrosis, operative, changes follow- 

 ing, 71, 72 



Asthenia in Addison's disease, 164 

 - following suprarenal suppression 



156 



Asthma thymicum, 122 

 Atropine, paralysis of vagal nerve 



endings by, 200 

 and pilocarpine, action compared, 



195 



Auto-intoxication in pancreatic dia- 

 betes, theory of, 423 



Auto-nephrotoxins, formation of, 443 



BARIUM chloride, action of, altered by 

 increase in doses of ergot, 231 



Basophile cells, 308 



Batrachians, suprarenal capsules in, 

 299 



Benzoic acid, affinity for glycocoll, 9 



Bile, secretion, increased by adrena- 

 lin, 212 



Biology, problems of, solved by 

 doctrine of internal secretions, 23 



Birds, acute tetany in, 41/42 



, castration in, results of, 378 



, heart of, action of adrenalin on, 

 202 



, perversion of sex characteristics 

 in, 365, 366 



, portal svstem of suprarenals pre- 

 sent in, 300 



, suprarenal capsules in, 128, 130, 

 133, 299, 300 



, thyroid apparatus in, 36 



Bladder, urinary effect of pituitary 



extract on, 326 



action of adrenalin on, 205 

 , experiments to determine, 205 



, innervation of, differences in mam- 

 mals, 205, 206 



, experiments to deter- 

 mine, 205 



Blood, action of thymus extract on, 

 121 



, adrenalin in, 250, 251 



, disappearance, 256-258 



, remaining after cessation of 



specific action, 258 

 , ultimate fate of, 255 

 , see also Adrenalsemia 

 , alkalinity of, disappearance of 



adrenalin under, 256 

 , changes in, following extirpation 



of suprarenals, 157, 158 

 , following thyroidectomy, 66 

 , cholesterinester in, source of, 292 

 , circulation of, and humoral path- 

 ology, 2 



in suprarenals of mammals, 



300, 301 

 , pulmonary, effects of adrenalin 



on, 185 

 , composition of, action of adrenalin 



on, 214 

 , effect of castration on, 388 



Blood formation, influence of thyroid 

 gland on, 37 



-, sugar-contents of, on what de- 

 pendent, 428 



, toxicitv after extirpation of supra- 

 renals, 156 



Blood-letting in tetany, 56 



Blood-pressure, action of adrenalin 

 on, 213 



, altered by previous adminis- 



tration of ergot, A3 1, 232 



of methylaminoketone on, 213 



, condition of, after extirpation of 



suprarenal capsules, 147, 148 

 , effect of intravenous injection of 



organic extracts on, 21, 22 

 - of pituitary extract on, 323 

 -of renal extract on, 442, 443 

 , fall of, induced by cholin, 276, 277 

 , increase induced by suprarenal 



extract, how abolished, 157 

 , intracranial conditions governing, 



329 



, permanent increase following con- 

 tinuous transfusion of adrenalin, 

 259 



, rise in, due to adrenalin, 183, 184 



Blood-serum, mydriatic, 262 



Blood-supply to kidney, action of 

 adrenalin on, 212 



Blood-vessels, contraction, drugs in- 

 ducing, 200 



, contraction following injection of 

 adrenalin, 196 



, dilatation, drugs inducing, 200 



, effect of pituitary extract on, 326 



, portion of, acted on by adrenalin, 

 187 



, pulmonary, effect of adrenalin on, 

 negative, 197 



, toxic action of adrenalin on, 240 



Boiling, activity of thymus extract 

 not affected by, 121 



Bones, changes in, in acromegaly, 333 



, growth of, effect of pituitary ex- 

 tract on, 328 



, influence of generative glands 



on, 382 

 Brain, blood-vessels of, dilated by 



adrenalin, 185 



, fourth ventricle, puncture of, and 

 experimental adrenalin-glycos- 

 uria, 219 

 - of pigs, lipoid substances in, 



290, 291 



-, relationship of tetany to, 60, 61 

 , weight of, in gigantism, 342 

 Bronchi, muscles of, action of adrena- 

 lin on, 208 



CACHEXIA, chronic, following thyroid- 

 ectomy, 63 



, following total thyroidectomv, 71, 

 72, 73 



, strumipriva and Graves's disease, 

 symptoms common to, 99 



