6oo 



INTERNAL SECRETION 



Parathyroid glands, extirpation, re- 

 sults, 38 

 , fat granules in epithelial cells, 



32, 33 

 . , iunction, 55 



, determination of, 18 



, functional derangement, 



diseases, following, 46 

 , glycogen in, 33 

 , histology, 32 



, preservation, at extirpation of 



goitre, 44 



- - , in relation to calcium meta- 

 bolism, 58 



, secretory function, 32 



, supernumerary, 35 



- , transplantation, 48 



- and thyroid gland, relationship 

 between, 51-55; see also under 

 Thyroid, gland 



Parathyroidectomy, effects of, 53, 54, 



55, 84 



, experimental, results, 41 

 , tetany following, 55 



with remnant of thyroid tissue left, 



result, 106 



Parietal eye in saurians, 351 

 Parkinson's disease, see Paralysis 



agitans 

 Penis, retractor muscle in rat, nervous 



network, 228, 229 

 Periphery, impressions conveyed from, 



to nervous centre, effect of, i 

 Peritoneum, lymphatics of, action of 



adrenalin on, 213 

 Phenylalanin, 297 

 Phlorizin, action on suprarenal-less 



dogs, 155 



and adrenalin, injection, effect on 



islands of Langerhans, 435 

 Phosphates in urine after removal of 



suprarenal capsules, 154 

 Phosphorus, excretion of, due to 



pituitary extract, 327 

 Phrenosin, 288 



Pigeons, effects of ligature of ex- 

 cretory ducts of pancreas on, 436 

 Pigment cells and granules of frog, 



action of adrenalin on, 214 

 Pigmentation, anomalies of, following 



extirpation of suprarenals, 157 

 , disordered, in Addison's disease^ 



164, 165, 168 

 . , effect of adrenalin on, 



165 

 Pigs, brain of, lipoid substances in, 



2QI 



, suprarenals of, lipoid substances 



in, 290, 291 



, thyroidectomized, changes in, 64 

 Pilocarpin, adrenalin-glycosuria in- 

 hibited bv, 226 

 _ effect on thyroid gland, 28 



- and atropine, action compared, 195 

 Pineal body, anatomy of, 351 



, clinical signs of diseases of, 



354 



Pineal body, embryology of, 351 



, histology of, 351 

 in new 7 born infants, 351 



, pathological anatomy of, 353 

 Pituitary body, see Hypophysis 

 - extract, action of, altered by in- 

 crease in doses of ergot, 231 

 , cardiac effects of, 323-325 

 - , characteristics of, 349 

 - , effect on circulatory system, 



323 



on metabolism, 327 



, hypotensive action of, 324, 325 



in acromegaly, 347 



, physiological activity of, 323 

 , toxicity of, 322 



, vasoconstrictor action of, 321, 



324 



gland, see Hypophysis 

 Pituitrin, mydriasis due to, 322 

 Placenta, extract of, effect on mam- 

 mary gland, 374 



, internal secretion of, 411 



Pneumothorax following experimental 

 extirpation of thymus, 117, 119 



Poisons, inorganic, resistance to, small 

 after thyroidectomy, 108 



Polyuria after extirpation of supra- 

 renals, 154 



following reduction of renal paren- 



chyma, 445 



Portal system of suprarenals 298, 299 

 - -in birds, 300 



in reptiles, 299 



Potential energy of organs of body, 



ii 



Precocity, sexual, 370 

 Pregnancy, enlargement of hypo- 

 physis during, 340 



, increase of weight of hypophysis 

 in, 307, 309, 3io 



- of suprarenal capsules dur- 

 ing, 269 



, interstitial ovarian tissue de- 

 veloped during, 400 

 , mammary growth during, 372, 375 

 , mydriatic blood serum in urine of, 



262 



Progeria, 75 



Prostate, effect of castration upon, 377 

 , hypertrophy of, cause of, 377 

 , internal secretion of, 410 

 Protagon, 286, 287 

 not a chemical entity, 290 

 Proto-adrenalin, see Adrenalin, pre- 

 cursors of 



Pseudo-hermaphroditism, 358, 362 

 , hypertrophy of suprarenals in, 269 

 Puberty, precocious, connection of 

 hypertrophy of suprarenals with, 

 270 



, sexual development at, 369 

 Pulse, effect of pituitary extract on, 



323-325 



Pupil, action of adrenalin on, 230 

 , dilatation of, effect of sympathetic 

 system on, 210 



