604 



INTERNAL SECRETION 



Tetany, following extirpation of thy- 

 roid gland, 38 



parathyroidectomy, 55 



, human, 44 

 , infantile, 45 



} causative factor, 120 



, localization of seat of, experi- 

 ;.< ments for, 59 



1 , undetermined, 61 



, post-operative, 44 



, treatment by parathyroid ex- 

 tract, 49, 50 



, puerperal, 44, 45 



- , relationship to brain and cere- 

 bellum, 60, 61 



to spinal cord, 60 



, symptoms of, latent, 45 

 ', toxin of, 55, 56 



, nature of, 56 



, point of attack, 59 



, treatment by blood-letting, 56 

 ** bv calcium salts, 58, 59 

 by immune serum, 56 



- by thyroid extract, 50, 5 1 

 Thomsen's disease, see Myotonia con- 



genita 

 Thoracic duct, excretion of lymph 



from, promoted by adrenalin, 



213 



, ligature causing glycosuria, 



43i 



Thymus extract, action of, 121 

 - -on blood, 121 

 , depressant, 121 



, tOxic, 121 



, activity not affected by boiling, 

 121 



gland, no 

 , anatomy, in 



^, cells of, not identical with those 



of lymph glands, 112 

 , development, 34. rii 

 r^~ : , enlargement in status thymico- 



lymphaticus, 122, 123 

 , extirpation, effect on nervous 



system, 120 

 site';.' , experimental, 115 



, effect on ossification, 117, 



118 



, followed by pneumo- 

 thorax, 117 



, hypertrophy in Graves's dis- 

 ease, 96 



, accompanying cardiac hyper- 

 trophy, 19 



, implantation, experimental, 

 119, 120 



- , normal weight in man, 113 

 , involution, 112 



, persistent and enlarged, follow- 

 ing thyroidectomy, 65 

 , physiology, 113 

 - , reaction of motor apparatus to 

 electric current, 120 



, relation of castration to,- 116 

 , relationship to hypophysis, 339 



Thymus extract, secretion, action as 

 disassimilatory hormone, 109, 

 1 10 



, size in dog, guinea-pig, and 

 rabbit, 113 



Thyroglobin, 29 



Thyroglobulin, 28, 31 



Thyroid apparatus, 26 



, influence on metabolism of 

 carbohydrates controlled by pan- 

 creas, 430 



, modification of action of 



adrenalin by, 226 



- extract, administration after sup- 

 pression of thyroid function, 86 



- in cachexia strumipriva, 87 



- in endemic cretinism, 87 

 , followed by hyperthyroid- 



ism, 90, 92, 93 

 by tachycardia, 90 



- in myxcedema, 87 



, oral, resistance to sub- 

 cutaneous injection of acetonitril, 

 increased by, 108, 109 

 , physiological effects, 89-92 



, antitoxic theory, 104, 105 



, diuretic action, 91 



, effect on metabolism, 91 



, favourable influence on tuber- 

 culous processes experimentally 

 produced, 108 

 - in myxoedema, 107 



, neutralizing activity, 108, 109 



, physiological effects on circu- 

 latory system, 89, 90 



, reduction of obesity by, 91 



, treatment by, mydriasis follow- 

 ing, 211 



gland, administration, effect on 



metabolic changes in hypothy- 

 rosis, 88 



anatomy, 26 



antitoxic activity, 108 



autotransplantation, 73 



chemistry of, 29 



colloid of, 27, 28 



comparative anatomy, 34-36 



development, 34 



diseases of, cause of pathologi- 

 cal conditions following, 107 

 , effect of adrenalin on, 28 



- of castration on, 344 



- on metabolism, 70 



; of nervous excitement on, 28 



- -of pilocarpin on, 28 



, etiological connection with 



Graves's disease, 100, 101 

 , extirpation, followed by hyper- 

 trophy of pituitary gland, 19 

 , function, secretory, negative, 

 104 



, positive, 104 



, suppression, 105 

 , histology, 26, 27 



/influence on blood-formation, 



37 



