detect primary proteoses, among the products formed, but 

 found deuteroproteose "B" (Pick) and peptone "A" (Pick). 



Magnus-Levy published results of a study of the digestive prod- 

 ucts of the Bence Jones protein, its reactions and content of 

 amid, diamino and monamino nitrogen. Huppert records results 

 of various elementary analyses that have been made of the 

 Bence Jones protein. Abderhalden and Rostoski made an 

 analysis of the Bence Jones protein with regard to its content of 

 the amounts of the various amino acids. Reach gives the 

 results of an analysis of the Bence Jones protein in terms of 

 its nitrogen partition. 



Zuelzer obtained the Bence Jones protein in the urine of 

 dogs poisoned with pyrodin (monoacetyl-phenylhydrazine), 

 a strong hemolytic agent. Stokvis found the Bence Jones 

 protein in the urine of dogs after its intravenous or rectal 

 injection. Matthes also found it in the urine of a dog after 

 the subcutaneous injection of the Bence Jones protein. EHinger 

 introduced 5 grams of the Bence Jones protein intravenously 

 in a dog but the urine yielded no precipitate with (NH 4 ) 2 SO 4 , 

 although the filtrate gave a strong biuret reaction suggestive 

 of peptone (Kuhne), which may have been derived from the 

 injected material. 



Allard and Weber found that the Roentgen ray treatment 

 of the bone tumor had no effect on the urinary output of the 

 Bence Jones protein. Voit and Salvendi report a case in 

 which diet modified the elimination of the Bence Jones pro- 

 tein, but Weber found that changes of diet had no influence 

 on its elimination in his case of multiple myeloma. 



Ribbinik and Askanazy could not find the Bence Jones 

 protein in the blood of a patient with multiple myeloma. 

 Coriat found the Bence Jones protein in a pleural effusion in 

 a patient suffering from multiple neuritis associated with 

 extreme tenderness of the ribs, while it was absent from the 

 urine. He found that on tryptic digestion it went into com- 

 plete solution. 



In a case of Weber's, microscopic section of some of the or- 

 gans showed the presence of a homogeneous hyaline substance 

 which he thought might possibly be the Bence Jones protein. 



