Chap. IX] 



SUMMARY 



159 



Clotting . 



Description 



Serum 



Clot 



Process 



Intravascular 

 Clotting 



Regeneration 

 of blood after 

 hemorrhage 



r Water. 



I Mineral salts. 



I Albumin. 



j Fibrin formed from fibrinogen. 



\ Corpuscles, red and white. 

 White corpuscles and blood- 

 plates disintegrate, and give 

 rise to prothrombin. Pro- 

 thrombin is acted upon by 

 calcium salts and forms 

 thrombin. Thrombin acts as 

 ferment or enzyme. 



Value Checks hemorrhage. 



Hemophilia . . Lack of coagulabihty of the blood. 



' A temperature higher than that of body, 



110-120° F. 

 Contact with any rough surface. 

 Contact with foreign substances. 

 Injury to the walls of the vessels. 

 Rest. 



Hastened by < 



Hindered by < 



' A very low temperature. 

 Contact with Uving tissues, especially 



blood-vessels. 

 Addition of acids, alkaUes, neutral salts, 



oils, ferments, water. 

 Absence of calcium salts. 

 Absence of fibrinogen. 

 Removal of fibrin. (Defibrinated blood.) 



^1. Circulating blood does not contain 



thrombin. 

 2. Circulating blood does contain throm- 

 bin, but it is counteracted by anti- 

 thrombin. 



r Injury to internal coat of blood-vessels. 

 I Any foreign material that will stimulate 

 I clotting. 



. Name given to clot which forms inside 



vessel. 

 . A thrombus that has become dislodged 



from place of formation. 



If immediate ill effects are counteracted by intravenous 

 infusion, plasma is regenerated rapidly, red corpuscles 

 in comparatively short time. 



Theories to 

 account for 

 rare occur- 

 rence 



Causes 



Thrombus 



Embolus 



