ORGANISATION AFTER SUPPURATION. 127 



were laid by pus-corpuscles wlilcli had not been set free. If wo 

 look for something analogous to this mode of epithelial develop- 

 ment, we can only compare it to the primordial separation of the 

 blastodermic tissue into epithelial and non-epithelial strata, and 

 so regard it as a true embryonic difterentiation. The adjoining 

 normal epithelium obviously cannot be deemed inert in the 

 matter ; it must be considered to exert some sort of " epithelial 

 infection " (§ 83). Indeed some such hypothesis is necessary to 

 explain the greater frequency (according to Heine and Billroth the 

 invariable occurrence) of cuticular cicatrisation from the margins. 

 The newly-formed epithelium always remains thin and diy. It 

 has never been hitherto observed to develope regular glands or 

 hairs ; on the other hand, I am able to state from personal know- 

 ledge that in some cases of epithelioma in scars, the peg-shaped 

 protrusions of epithelium characteristic of this form of tumour 

 start from the thin cuticle of the cicatrix. 



• § 105. These are the outlines of formative inflammation, 

 when this runs its entire course in the intermediate apparatus of 

 nutrition, and is combated by its means alone. Various modifi- 

 cations of great interest and importance are determined by the 

 peculiar structure of the individual organs, and must therefore 

 be reserved for consideration in the Special Part of this work. 

 In this place I will only allude once more to that singular devia- 

 tion from the normal course of repair by second intention which 

 consists in the growth of the so-called '' proud flesh." 



The caro luxurians may be defined as an overgrowth of the 

 granulations. Instead of little warty prominences, which ought 

 not to exceed a line in height or in breadth, we have fungous 

 masses cropping uj^, characterised by being three or four times 

 larger than ordinary granulations, partially dendritic in form, 

 highly vascular, and possessing a certain joower of resisting 

 external influences. These funo-ous cfranulations are distin- 

 guished histologically by a peculiarly, high degree of differentia- 

 tion of the embryonic tissue. In the first place, we have a more 

 elaborate stroma throughout, a stroma resembling that of the 

 lymphatic follicles. It is formed partly by the interstitial 

 cement of the connective tissue, which fills up the lacunar net- 

 work betw^een the spheroidal cells : this stiffens into fine cylin- 

 drical threads : partly by a certain number of the cells them- 

 selves. These assume a stellate form, and constitute the nodal 



