TUBEECLE, 



137 



work. I must confine myself at present to what is really the 

 same in all cases, sc. the minute structure of the grey miliary 

 nodule, and what we know about its genesis. 



§ 114. If we teaze out a miliary tubercle with cataract- 

 needles, w^e readily succeed in isolating the following elements : 



Fig. 43. 



L-'^M^'^^^ 



•-© 



^w 





"^ox:i 



Ky 



Elements slio-wn by teazing out a miliary tubercle. 1. The 

 large tubercle-cells ; 2. The small tubercle-cells ; 3. Endo- 

 genous cell-development; 4. Delicate reticulum from the 

 interior of a miliary tubercle ; the cells partly removed by 

 pencilling ; 5. Shreds torn from the adventitia of a small 

 cerebral vessel in the neighbourhood of a miliary tubercle. 

 Fission of the nuclei on the inner surface of the adventitia ; 

 finely-granular protoplasm accumulated in a continuous 

 layer of considerable thickness ; 6. Development of tubercle- 

 cells ; 7. The border of a minute vessel, showing the deve- 

 lopment of tubercle-cells in its adventitia. 



1. (Fig. 43) — Large cells, either round, or more often 

 roundly-polygonal, consisting mainly of a finely-granular, highly 

 refracting, seemingly very dense material. The sharp outline, 

 i.e. the smooth surface by which the cell is bounded, leads us to 

 assume the existence of a cell-membrane, although this cannot 

 be demonstrated by the appropriate methods (addition of water, 

 crushing, detection of a double contour, &c.). Most of them 



