148 ROUND-CELL SARCOMATA. 



^vo may affirm generally that growth by infiltration of surround- 

 ing tissues, the so-called peripheric mode of growth, occupies a 

 subordinate position ; central growth, increase by internal appo- 

 sition, taking the first place. The fibromata afford exquisite 

 examples of central growth ; the medullary round-cell sarcomata 

 incline rather to the peripheric mode of increase ; the spindle- 

 cell sarcomata, in this as in other respects (^sc. as regards malig- 

 nity) occupying an intermediate position. 



It would be possible to constitute a long series of species 

 and sub-species of sarcomata, were all those modifications to bo 

 taken into account which are mainly due to the seat of the 

 tumour. I prefer to confine my remarks to a limited number 

 of typically recurring forms, and to relegate the consideration 

 of the special sarcomata of individual organs and systems to 

 the second part of this treatise. Among such special forms I 

 place the ossifying sarcoma of the periosteum and the giant- 

 cell sarcoma of the medulla of bone, the glioma of the central 

 nervous organs, the cystosarcomata of the various glands, &c. 1 

 will also avoid all reference at present to the finer shades of 

 difference between the leading forms ; in my own experience, 

 there is hardly any tumour which has not some shade of differ- 

 ence peculiar to itself; nay, I would go so far as to assert, that 

 tumours exactly similar to one another can only occur at exactht 

 the same point in the organism. 



Round-cell Sarcomata. 



§ 124. I. — 21ie granulation-like round-cell sarcoma (sarcoma 

 lobo-cellulare simplex). In texture and composition this form of 

 sarcoma approximates most nearly to the type of granulation- 

 tissue. It presents itself to the naked eye as a yellowish or 

 reddish mass, homogeneous throughout, soft yet clastic, and occa- 

 sionally very like fish-roe ; from its cut surface a scanty juice 

 may be scraped ; this juice is nearly clear, or else contains but a 

 small proportion of cells. The cells are small in size, round, and 

 contain relatively large, sharply-defined nuclei, furnished with 

 nucleoli. As a rule, there is but little protoplasm, and what 

 little there is is quite naked ; to make it visible, and to convince 

 ourselves that each of the seemingly free nuclei is really part of 



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