150 



ROUND-CELL SARCOMATA. 



cells -with large, oval nuclei, Avliicli refract light but feebly, and 

 are each provided with a j^oint-like nucleolus. On hardening 

 the tumour and pencilling out a fine section, avc discover a deli- 

 cate intercellular network, which forcibly reminds us of the 

 reticulum of the lymphatic follicles, the alimentary mucous mem- 

 brane, and the caro liLTurians (fig. 45 J. This network is stretched 

 between the wide, thin-walled capillaries, and imparts a certain 

 consistency to the entire structure, while permitting fluid to 

 collect in abundance round the cells, and thus favouring their 

 isolation. 



This form of sarcoma originates most frequently from the- 

 subcutaneous, subfascial, and intermuscular connective tissue of 

 the thigh. Xext in order of frequency come the lymphatic 

 glands. In this case however we are met by the singular diffi- 

 culty that the anatomist may be misled by similarity of structure 

 into regarding the sarcoma as a simple overgrowth, however 

 monstrous, of the glands ; while its clinical mark (one of extreme 

 malignity) indicates its absolute identity with the soft variety of 

 sarcoma. (^See Lymphatic Glands.) 



Fig. 45. 



Round-cell sarcoma, a. Lumina of vessels ; l. Parenchyma 

 partially pGncilled out to sliow the delicate network formed 

 by the hardened matrix, y^^. 



There are several varieties of the lymphadenoid sarcoma. 

 The Upomatoiis variety (sarcoma lipomatodcs) is characterised by 



