152 



ROUND-CELL SARCOMATA. 



approximation of its cells to the epithelial type, and by an inter- 

 cellular network Avitli meshes of proportionate size (fig. 46). 

 This tumour is very soft, cerebriform, and therefore easily con- 

 founded with the next species. 



Fig. 46. 





The large-celled round-cell sarcoma, -iuu- (After Billroth). 



III. — The alveolar round-cell sarcoma {Bilbvth) (sarcoma 

 mcdullare, carcinomatodes) represents a farther advance in the 

 independent evolution of the cells, analogous on the one hand 

 to the suppuration of an inflamed texture, while on the other it 

 recalls that more sharply-defined contrast between the connective 

 tissue and the corpuscular structures which we shall find in 

 cancer. Characteristic of this variety is the occurrence of 

 globular masses of cells, which are no longer held together by 

 any proper matrix, but resemble the pus-corpuscles of a minute 

 abscess in occupying a gap of appropriate size in the continuity 

 of the connective tissue. This must not be taken to imply that 

 the cells in any way resemble pus-corpuscles ; on the contrary, 

 they are notably larger in size, they are provided with round, 

 vesicular nuclei containing lustrous nucleoli, and verge far more 

 nearly on the epithelial type, which in solitary instances they 

 may even simulate in the most deceptive way. And here I go 

 farther than many will be disposed to follow me ; I regard the 



