CABCINOMA. 243 



istic changes which the cells of the reticulum in their neighboui'- 

 hood have undergone, as a result of ^^ epithelial infecti(^n"; for 

 they increase in size, and their anastomoses become broader, the 

 final result of these changes being a structure (fig. 76) which recals 

 in some degree that of the secreting network of the liver. The 

 frequent occurrence of double nuclei points to an independent 

 multiplication of the cells by fission. In the face of this appear- 

 ance, and of the fact that the alteration is only met with in the 

 neighbourhood of matm'e, concentrically laminated epithelial cells, 

 can we hesitate to believe that the cells of the reticulum are 

 actually converted into epithelial cells ? I ought to add, that the 

 retiform structure persists for a long time, and may even be 

 demonstrated in cancroid nodules which are large enough to be 

 recognised by the naked eye. 



