CONDYLOMATA. Ml 



tliat of ordinary warts ; but in addition to the terminal, there is 

 also a lateral apposition of young connective tissue, a dilatation 

 and elongation of the capillary loops. An arborescent stroma of 

 connective tissue is thus produced, whose outlines are repeated 

 on a larger scale by the epidermic stratum. 



§ 310. The smaller papillomata, such as the porrum, are very 

 closely related, at any rate in outward form, to the pointed 

 CONDYLOMATA. These too are destitute of a common covering 

 for the thickly-set, hyperplastic papillae of the skin. They grow 

 in just the same way, save that, as Biesiadeckl has shown, a 

 histological factor, which is of secondary importance in tlie 

 normal growth of epithelium, takes a more prominent part in 

 the development of acuminated condylomata. I allude to a 

 certain fission of the epithelial cells, which is exclusively observed 

 in the middle stratum of the epidermis — wdiere cornifieation has 

 not yet begun. The effect of this secondary growth of epithe- 

 lium is barely appreciable in the normal development of the 

 epidermis ; to it we may ascribe the peculiar swelling of the 

 epithelial border (fig. 39, e) which occurs during the skinning- 

 over of granulating wounds ; but it contributes most effectually 

 to increase the thickness of the epithelial protrusions in epithelial 

 cancer ; in the pointed condylomata the extreme softness of the 

 epidermic covering arrests attention, and this is due to the ex- 

 cessive development of the mucous layer. The red and fleshy 

 aspect of the sycomata, which impart a sensation almost like 

 that of mucous membrane to the finger, is also due to the fact 

 that there is no thick horny layer to mask the colour and con- 

 sistency of the young and vascular connective tissue. 



Flat condylomata (^Condylomata lata, Plaques inuqueuses), 

 must be sharply distinguished, in a histological point of view, 

 from the pointed variety. The overgrowth of the papillar}^ bod\' 

 is more diffuse ; it is not confined to the tips of the papilla), 

 as in the papillomata just described. The overgrowth of the 

 connective tissue predominates over that of the epidermis. Flat, 

 rounded elevations about one line in height and from two to 

 five lines in breadth, are thus produced ; upon their surfi^ce 

 the papillae form secondary prominences. The colour of these 

 condylomata varies from a pale to a dirty red ; their epithelial 

 layer is exceedingly thin ; it is only in the folds between the 

 adjacent prominences that a sort of cheesy epithelial substance 



