SULPHUROUS ACID AND SULPHITES. 773 



The subject was all right with the exception of a slight feeling of 

 weakness. On the next day his temperature and pulse were exactly 

 the same as on February 21. He was feeling very tired, although 

 he had not taken any extra amount of exercise; lips were dry and 

 parched and he had a bad taste in his mouth. He did not experience 

 so much trouble from indigestion as on the preceding few days, but 

 was troubled with quite severe heartburn. On February 23 his 

 temperature and pulse were normal, 98.4 and 76, respectively. He 

 reported "abdominal pains" and expulsions of gas during the day. 

 He was feeling much better the next day, but on February 25 was 

 quite uneasy again; had a very restless sleep and a return of pains 

 in stomach, also dizziness. His temperature and pulse for this day 

 were 97.9 and 80, respectively. His average body weight for the 

 third preservative subperiod was 64.39 kilograms. 



On the first day of the fourth preservative subperiod No. 3's tem- 

 perature was 99.4 F. before dinner and 100 F. after dinner; pulsa- 

 tions, 100; he had decreased considerably in weight from the previous 

 day and reported that he had had severe dizziness during the evening 

 and day and another attack of palpitation, became nauseated, and 

 had an attack of vomiting during the afternoon. The administration 

 of the preservative was discontinued from this time on, but for the 

 remainder of this period the same symptoms were noticeable, particu- 

 larly a feeling of dizziness and pains in abdomen. 



The last day of the preservative period No. 3 reported himself as 

 " feeling good." His temperature was 98.90 F., pulse 72, and body 

 weight 64.32 kilograms. The average body weight for this subperiod 

 was 63.51 kilograms. 



The average body weight for the entire preservative period was 

 64.07 kilograms, a little higher than the average for the fore period, 

 but a glance at the daily platted weights (fig. 1) shows a marked 

 falling off in weight corresponding to the large administration of pre- 

 servative and an increase in weight when the preservative was with- 

 drawn. The subject showed the effects of the preservative to a marked 

 degree. His general appearance at the end of the preservative period 

 was much below normal, his color was not good, and he was in a much 

 depressed condition. He was quite ill on February 26, and though 

 somewhat alarmed, the fact that he was a senior medical student 

 would permit of full credence being given to the symptoms as he 

 described them. The urine examination during the preservative 

 period showed a minute trace of albumin at end of period. 



In the first part of the after period the symptoms of digestive dis- 

 turbance were still recorded by No. 3. The last part of the first 

 subperiod he reported himself as feeling well. His temperature and 

 pulse, which had been somewhat irregular, returned to normal, 98.6 F. 



