SULPHUROUS ACID AND SULPHITES. 785 



noon. The feeling of weariness and fatigue continued to such an ex- 

 tent that the subject had some difficulty in performing his work, 

 and headache continued during the day. Temperature and pulse 

 were normal throughout this subperiod. The body weight averaged 

 69.57 kilograms. 



No. 12 had a headache throughout the third preservative sub- 

 period. He also complained and had noted on several occasions that 

 immediately after taking the preservative sharp pains would appear 

 in his head, which would last from one to four hours. The taking 

 of the preservative gradually became more and more irritating to the 

 throat, an observation made by several of the subjects. On the second 

 day of the subperiod he had a headache and felt tired, though he had 

 not exercised as much as usual. The tired and weak feeling con- 

 tinued on the next day, February 23, with pain in stomach and 

 head; complained on next day of pains in region of kidneys, heavy 

 sensation in stomach, and the usual headache. On February 25, the 

 last day of the period, he recorded that he had passed a very uncom- 

 fortable night; had pains in stomach and intestines; felt very weak 

 and exhausted and had a severe headache during the day. His 

 average weight for this period was 69.70 kilograms. 



No preservative was given No. 12 during the fourth preservative 

 subperiod. The headache, pains in region of kidneys, and general 

 feeling of weakness continued. His general appearance was consid- 

 erably below normal; his temperature appeared to be slightly lower 4 

 during this period; pulse normal. A slight trace of albumin was 

 detected in the urine in the fourth preservative subperiod, which con- 

 tinued during the after period. The average weight for this sub- 

 period was 69.63 and 69.67 kilograms for the entire preservative 

 period. 



In the first after subperiod No. 12 on the first day felt weak, espe- 

 cially in the back in the region of the kidneys. He felt very well 

 the following two days, with appetite gradually improving; on the 

 last day, however, his appetite was not so keen. The body weight 

 for this subperiod was 69.70 kilograms. 



During the second after subperiod his appetite gradually returned, 

 and he reported himself as feeling very well, but occasionally weak 

 and tired at night. On the first day of this subperiod it is noted that 

 for the week preceding he had suffered considerably with irritable 

 kidneys and bladder. At times he had no control over the bladder 

 and passed urine almost involuntarily. His general appearance was 

 considerably improved at the end of the after period, though he was 

 quite slow in getting back to a normal condition again. The average 

 body weight for this period was 69.62 kilograms, the same as in the 

 preservative period, and a slight gain over the fore period, the weight 

 being very constant 



r THE 



VERSITY 



