SULPHUROUS ACID AND SULPHITES. $21 



The data for No. 1 show an average excretion of 1,109 cc per day 

 in the fore period and 969 cc in the preservative period, indicating 

 a considerable diminution in the volume of urine. In the case of 

 No. 2 the average quantity of urine excreted in the fore period is 1,296 

 cc and in the preservative period 1,150 cc, showing again a decided 

 decrease in volume. In the case of No. 3 the average quantity of 

 urine excreted in the fore period is 1,053 cc and in the preservative 

 period 1,142 cc, showing a marked increase. 



These three men received sulphurous acid in the form of sodium 

 sulphite. For Nos. 4, 5, and 6, who received sulphurous acid in the 

 form of a gas in solution, the following results were obtained: 



In the case of No. 4 the average quantity of urine excreted in 

 the fore period is 687 cc and in the preservative period 1,028 cc, 

 showing a marked increase. In the case of No. 5 the average quan- 

 tity excreted in the fore period is 1,198 cc and in the preservative 

 period 1,170 cc practically no change in volume. In the case of 

 No. 6 the average quantity of urine excreted in the fore period is 

 953 cc and in the after period 1,080 cc, showing a marked increase. 



SUMMARIES. 



The summary for Nos. 1, 2, and 3, receiving sodium sulphite, shows 

 the average quantity of urine excreted in the fore period to be 1,153 

 cc and in the preservative period 1,087 cc, a notable decrease in 

 volume. In the case of Nos. 4, 5, and 6 the average quantity of urine 

 excreted in the fore period is 945 cc and in the preservative period 

 1,093 cc, showing a notable increase. 



The summary for the six subjects shows that the average quantity 

 of urine excreted in the fore period is 1,056 cc and in the preservative 

 period 1,090 cc, showing only a slight increase in volume. 



The data in regard to the volume, while not showing as distinct a 

 diuretic effect as in the original series, still shows some relationship. 

 In the average for Nos. 1, 2, and 3, who received sodium sulphite, 

 there is seen some tendency to diminish the quantity of urine excreted 

 during the preservative period. On the other hand, in the original 

 series an increase in the volume is observed. The quantity of pre- 

 servative administered, it may be well to note, was considerably 

 smaller during the preservative period of this special study than 

 during Series VII a fact which probably influenced the results con- 

 siderably. Nevertheless, ifi the case of those subjects receiving 

 sulphurous acid there is seen a slight increase in the volume during 

 the preservative period, which seems to bear out the conclusion indi- 

 cated in the original study, namely, that free sulphurous acid exerts 

 more of a diuretic effect than when administered as sodium sulphite. 



