146 



STUDY AND IDENTIFICATION OF MOULDS 



produced a monilia septicemia in rabbits inoculated with the sprue fungus. This 



fungus is quite pathogenic when first isolated from sprue lesions. 



In internal organs the mycotic areas are not associated with pus formation. On 



two occasions he has produced stomatitis in animals by feeding experiments. 



Monilia tropicalis. Castellani has reported this fungus as the cause of a broncho- 

 mycosis. It does not coagulate milk nor liquefy gelatin. The growth on 

 Sabouraud's medium is mainly of yeast-like cells. 



M . Candida. This fungus was found in white patches on tongue of 

 a child. The conidia are 7 to 8 microns and the mycelium i to ij^ mic- 

 rons in diameter. 



Boggs has recently isolated a Monilia which he considers as closely related to 

 M . Candida. The patient was at first thought to have a mammary carcinoma with 

 axillary gland metastases. Later on there was a severe cough with abundant red- 



FIG. 43. Thrush fungus. (Kolle and Wassermann.) 



dish-gray sputum which showed mycelium and yeast-like cells. Cultures on glucose 

 agar, potato, etc., at 37C. and at room temperature gave a moist glistening 

 whitish growth which, when examined, showed only yeast-like cells, no mycelial 

 growth. Hyphae only showed in later cultures. 



There was a fair growth in milk with after three or four weeks an alkaline reac- 

 tion and firm coagulum. Slight acid production in glucose but none in lactose, 

 saccharose or mannite. 



Mycelial growth was more rapid in anaerobic cultures than in aerobic ones. 

 Boggs notes that his Monilia is morphologically indistinguishable from the Monilia 

 of sprue. The buccal mucosa of this case did not show any abnormalities. 

 Trichosporum giganteum. This is the cause of a disease of the hairs, known in 



Columbia as "Piedra," so called from the small gritty-like masses along the 



length of the hair. These spores are arranged like mosaics about the hair. 

 Sporotrichum beurmanni. This fungus has a narrow mycelium (2/1) and branches 



in all directions. The spores appear as little grape-like clusters of oval spores 



