

SPLENIC ANAEMIA 241 



Banti's disease but pathologically the spleen shows a fibrosis instead of the marked 

 increase in lymphatic tissue characteristic of Banti's disease. 



In the tropical splenomegaly or kala-azar we have a marked leukopenia with 

 a marked reduction in the percentage of polymorphonuclears. The Gaucher type 

 of splenic anaemia does not show as pronounced and early an anaemia as in Banti's 

 type. 



Certain conditions which partly resemble myelogenous leukaemia 

 and partly pernicious anaemia are designated leukanaemia. Some con- 

 sider this to belong to the group of diseases in which the multiple 

 myeloma is placed. 



In splenomegalic polycythaemia we have a red count of from 9,000,000 to 10,000,000. 

 The Hb. percentage may be 200. There is also a leukocytosis up to 50,000. Pa- 

 tients are cyanosed and have a very large spleen. 



Splenic anaemia of infancy usually occurs between the ages of twelve and twenty- 

 four months. The spleen is notably enlarged and in many cases the liver is equally 

 so. The red cells are not greatly diminished in number, 2,500,000 to 3,000,000 

 being usual findings. Nucleated reds are abundant. While a leukocytosis of 

 30,000 to 50,000 is often present it is markedly less than that of splenomyelogenous 

 leukaemia and the increase in white cells is more of those of lymphocyte type. 



The color index is very low. 



Another splenomegaly of children, clinically resembling kala-azar, is caused by 

 Leishmania iufantum. 



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