344 



INFECTIVE DISEASES. 



Frankel and Simmonds inoculated a number of rabbits in the vein of 

 the ear, producing death, in some cases .in forty-eight hours. Seitz 

 administered broth-cultures by Koch's method of introducing them 



into the stomach after 

 the administration of 

 opium in guinea-pigs, 

 and death resulted in 

 several instances. 

 But in all these cases 

 the results depended 

 upon the poisonous 

 products found in the 



FIG. 133. COLONIES OF TYPHOID BACILLUS. 

 Three days old. x 100 (FRANKEL AND PFEIFFER). 



cultivations, a similar result following the 

 injection of sterilised cultures. An account of 

 the products has already been given (p. 41). 



Cassedebat isolated three species of bacilli 

 from water, which could be distinguished 

 with great difficulty, and only after the most 

 careful comparison. The bacillus which most 

 closely resembles it is the Bacillus coli com- 

 munis; in fact, Boux regards it as a non- 

 pathogenic variety of the typhoid bacillus. 

 Others claim to be able to distinguish it by 

 careful comparison and the application of 

 tests. Special importance is attached to 

 potato cultures, the typhoid bacillus forming 

 an invisible film, and Bacillus coli communis 

 a well-marked yellowish growth. Terni 

 pointed out that Bacillus typhosus retains its 

 motility in media containing hydrochloric 

 acid, while Bacillus coli communis and other bacilli resembling those 

 of typhoid lost their motility. Schild maintained that Bacillus typhosus 



FIG. 134. PURE- CULTURE 

 OF TYPHOID BACILLI 

 INOCULATED IN THE 

 DEPTH OF NUTRIENT 

 GELATINE (BAUMGAR- 

 TEN). 



