150 



PHYSIOLOGICAL CHEMISTRY 



Ewald and Boas, 1 Reichmann, 2 v. Jaksch, 3 Kornemann, 4 Schule 5 and 

 Gregersen 6 followed a similar procedure. The first report of data from 

 the entire gastric cycle obtained by means of a small bore tube were 

 made by Ehrenreich. 7 This investigator used a Nelaton catheter. 

 Skaller 8 has reported a few experiments in which a small bore stomach 

 tube with a metal tip was employed and the stomach contents 

 subjected to fractional analysis. 



Until recent years, the concensus of opinion based principally upon 

 the work of the Pawlow school 9 was to the effect that the gastric juice 



8 



20 40 60 80 100 IZOminotes 



Diet. 100cc.of- 0.542 7oHCl at23C 



F G. 43. INFLUENCE OF ACID INTRODUCED INTO THE NORMAL HUMAN STOMACH. 

 (Spencer, Meyer, Rehfuss and Hawk: American Journal of Physiology, March, 1916.) 



of normal man had an average acid concentration of 0.2 per cent 

 hydrochloric acid, whereas the gastric juice of the dog and cat had an 

 average acid concentration of 0.4-0.5 per cent hydrochloric acid. 

 These experiments were based principally upon the examination of 

 the pure gastric juice of the lower animals as compared with the stomach 



1 Ewald & Boas: Virchow's Arch., 101, 325, 1885. 



2 Reichmann: Zeit. f. klin, Med., 24, 565, 1885. 

 8 V. Jaksch: Zeit. f. klin. Med., 19, 383, 1890. 



4 Kornemann: Arch. f. Verdauungskr., p. 369, 1912. 

 6 Schule: Zeit. f. klin. Med., 27, 461, 1895. 



6 Gregersen: Arch. f. Verdauungskr., 19, 263, 1913. 



7 Ehrenreich: Zeit.f. klin. Med., p. 231, 1912. 



8 Skaller: Berl. klin. Woch., 50, No. 47, 1913- 



9 Pawlow: The Work of the Digestive Glands. Translated by Thompson, Second Edition, 

 1910. 



