METABOLISM 



S67 



(b) Influence of Starch. Repeat the experiment as given above for glucose 

 except that 170 grams of whits bread or 100 grams of starch made into a paste 1 

 are substituted for the 100 grams of glucose. 



The experiment may be repeated as described above using an increased 

 amount of starch. 



The various experiments may be conducted on patients suffering from dia- 

 betes mellitus if such are available and instructive data collected. The alimen- 

 tary hyperglycemia will generally be more prolonged than hi the case of normal 

 subjects. 



4. Influence of Physical Exercise upon Blood Sugar. After strenuous physical 

 exertion by a normally nourished individual there is an increase in the sugar concen- 

 tration of the blood. 2 Similar increases are not shown by resting individuals simi- 

 larly nourished nor by fasting individuals after strenuous physical exercise. This 

 point is illustrated in the following protocol : 



INFLUENCE OF PHYSICAL EXERCISE ON BLOOD SUGAR (Normal Man) 



Fasting. 



Fasting and 2 -hour march (8 miles). 



7A.M. 



12 A.M. 



0.047 



0.052 



The increase in blood sugar under the influence of exercise occurs rather sooner in 

 the diabetic organism. Typical data follow: 



Experiment. Ingest a simple uniform diet (see Experiment 34, page 592) for 

 five days taking the first meal after 12 o'clock (noon) and the last one before 10 

 P. M. On the morning of the second day (7 A. M.) determine the sugar in your 

 blood (see methods, Chapter XVI). About three hours later take a brisk walk 

 for 8 miles covering the distance in about two hours and consume 200 grams 

 sucrose during the walk. Make a second analysis of the blood sugar. On the third 

 day analyze your blood for sugar at 7 A. M. and again at noon, remaining quiet in 

 the meantime. The fourth day should be passed without physical exertion \vhereas 

 on the second day between 10 A. M. and 12 M. a brisk 8-mile walk is taken but no 



1 In making starch paste, rub up the dry starch in a mortar with cold water and pour the 

 suspended starch granules into boiling water and stir. 

 2 Moraczewski: Bioch. Zeit., 71, 268, 1915. 



