lot) 



INFECTIOUS LEUKAEMIA 



Attention should be called to the fact that as yet there 

 seems not to have been a careful study of the condition of the 

 blood in fowl cholera. Salmon observed many changes in this 

 fluid which may have been similar to or identical with those 

 herein recorded. 



The difference betvi'een the specific organism of these two 

 diseases can be readily appreciated by a comparison of the 

 more diagnostic properties of each ; they are arranged in par- 

 allel columns, as follows : 



Bacterium of fowl cholera. 



1. Bacterium short, with oval 



ends. 



2. It usually appears singly in 



tissues. 



3. Ordinarily it exhiVjits a polar 



stain. (From tissue. ) 



4. Grows feebly or not at all on 



gelatin. 



5. It does not change milk. 



6. Resists drying from one to 



three da}'s. 



7. Kills rabbits inoculated sub- 



cutaneously in from eigh- 

 teen to twenty-four hours. 



8. It kills fowls when injected 

 subcutaneously in small 

 quantities. 



5- 

 6. 



Bacterium satiguhiai-ium. 



Bacterium short, with ends 

 oval or more pointed. 



It usualh' appears in pairs 

 united end to end or in 

 clumps in tissues. 



It gives a light center, with 

 uniformly stained peri- 

 phery. (From tissue.) 

 Rarely a polar stain is 

 observable. 



Decided growth on alkaline 

 gelatin. 



Saponifies milk. 



Resists drying from eight to 

 twelve days. 



Kills rabbits inoculated in- 

 travenously in from three 

 to five days. Rabbits in- 

 oculated subcutaneously 

 remain well or die in from 

 six to ten days. 



It does not kill fowls when 

 injected subcutaneously 

 in small quantities. 



While there are many similarities in the symptomatology 

 of these two diseases, there are pronounced differences in the 

 morbid anatomy and in the specific microorganisms. These 

 facts will render the positive differentiation dependent upon a 

 careful bacteriologic and pathologic examination. In fowl 

 cholera the course of the disease is more rapid than in leu- 

 kgemia. 



