MORBID ANATOMY I 79 



from without. To illustrate more fully the differences in the 

 lesions of the two forms of the disease, the published post- 

 mortem notes of two cases are appended. 



(i) Acute form. Female, two years old, weight about 250 pounds. 

 She had been known to be sick but a few hours. The examination was 

 made two hours after death. A littte blood was oozing from the nostrils. 

 The skin was not discolored. Upon section the flesh was normal in 

 appearance. The liver was deeply reddened due to engorgement of the 

 blood vessels. Blood flowed freely upon section. The spleen was 

 slightly enlarged and dark colored. The kidneys were hyperaemic, 

 especially the mc-dullary portion. In the pelvis of the right kidney 

 there was a large blood clot. The mucous membrane of the intestines 

 was normal with the exception of several irregular areas of hyperaemia. 

 In the fundus of the stomach was a large, dark blood-clot. No ulcers. 

 The mesenteric glands were enlarged and darker than normal. In a few 

 cases the cortex was hemorrhagic. The right lung was in a state of 

 hyperaemia. The heart contained very little liquid blood. 



Bacteriological exiDuination. — A few bacteria were found in stained 

 cover-glass preparations from the spleen and liver. Tubes of slant 

 agar were inoculated with bits of the tissue from the hyperaemic lung, 

 liver, spleen and kidneys. These tubes developed cultures of the hog- 

 cholera bacillus. A few of them were pure cultures; the others con- 

 tained, in addition to the hog- cholera organism, a quite large bacillus. 

 (Report N. Y. State Com. Agric. 1887) 



(2) Chro7iic form. Small female, weight about 50 lbs. Considerable 

 reddening of the skin over the ventral aspect of the body and limbs ; 

 especially marked along the median line. Superficial inguinals enlarged, 

 of a mottled, pale and deep red on section. Spleen very large, 12 inches 

 long, 2 inches broad, and five-eighths to three fourths inches thick at 

 the hilus ; gorged with blood, friable. A small number of punctiform 

 hemorrhages in cortical portion of the kidneys. Glands of mesentery 

 and colon enlarged and congested. Deep reddening of several square 

 inches of mucosa in fundus of stomach. Large intestine contains a semi- 

 liquid mass chiefly earth. Four large ulcers in the caecum, one of them 

 at least one inch across, covered by a yellowish slough ; the peritoneum 

 covering it is thickened and inflamed. In upper colon there is consider- 

 able necrosis, involving the epithelium in patches. Lungs normal, 

 excepting the right ventral lobe, which is solid. Bronchi and air cells of 

 this lobe completely occluded by plugs ; surface bright red, mottled with 

 yellowish points — the ultimate air cells filled with the cellular exudate. 

 Subpleural ecchymoses over both lungs. From the spleen a liquid and 

 a gelatin culture contained only hog cholera bacteria. They were verj- 

 numerous in cover-glass preparations from this organ. 



A rabbit inoculated from the consolidated lung tissue died on the 



