MORBID ANATOMY 269 



like exudation in the connective tissue of the throat, chest 

 and abdomen, about the muscles and other tissues, and 

 especially round the base of tlie heart. The lungs often show 

 sio;ns of inflammation. The mucous membranes and other 

 tissues are frequently tinged yellow by the coloring matter of 

 the bile. 



Steel noticed ulceration of the stomach in about two-thirds 

 of his cases among mules in Burma. In India this ulceration 

 has not been observed among horses as a sequence of surra. 



The clinical aspect of surra is essentially one of progres- 

 sive anaemia, accompanied by paroxysms and intermissions, 

 during both of which there is a gradual decrease in the num- 

 ber of the red blood corpuscles and in the amount of hemo- 

 globin in the blood, with consequent anaemia of the visible 

 mucous membranes. 



The importance of this disease renders it desirable to 

 reprint "A preliminary note on a parasitic disease of horses," 

 by Capt. Allen M. Smith and Dr. J. J. Kinyoun from the 

 Army Pathological Laboratory, Manila, Oct. 17, 1901, as it 

 gives a good idea of the appearance of the disease. The 

 accompanying photograph showing trypanosoma was taken 

 by Smith and Kinyoun at that time. 



"On October 15, 1901, information was given us by J. W. Jobling, 

 Assistant Bacteriologist of the Board of Health of Manila, that an epi- 

 demic sickness of an undetermined nature was now prevailing in this 

 city, and also that he had just taken a specimen of blood from a sick 

 animal which on examination revealed the presence of a parasite, 

 whether this was accidental or was the causative agent of the disease in 

 question, he was unable to say. On investigation and enquiry it was 

 learned from the Veterinarian in charge of the corral of the Quarter- 

 masters Department, and from the City Veterinarian, that there was now, 

 and had been, a fatal epidemic among the horses in Manila, the Quarter- 

 masters Department having lost over 200 within the past four months. 



One of the corrals was visited by us on the 15th inst., where we were 

 shown, by the Veterinarian in charge, 20 horses and mules, ill with an 

 undetermined disease. These animals presented the several stages of 

 the malady, some were quite recently attacked, while others had been ill 

 for over two months. 



The symptoms first noticed are : impairment of appetite, constipa- 

 tion, fever and' thirst. These are followed within a few days by a rapid 

 and progressive emaciation. 



