286 BACTERIOLOGY. 



THE LESS COMMON PYOGENIC ORGANISMS. 



The organisms that have just been described are 

 commonly known as the "pyogenic cocci" of Ogston, 

 Rosenbach, and Passet, and up to as late as 1885 were 

 believed to be the specific factors concerned in the pro- 

 duction of suppurative inflammations. Since that time, 

 however, there has been considerable modification of 

 this view, and while they are still known to be the 

 most common causes of suppuration, they are also 

 known not to be the only causes of this process. 



With the more general application of bacteriological 

 methods to the study of the manifold conditions coming 

 under the eye of the physician, the surgeon, and the 

 pathologist, observations are constantly being made 

 that do not accord with the earlier ideas upon the 

 dependence of all forms of suppuration on invasion by 

 the pyogenic cocci. There is an abundance of evi- 

 dence to justify the opinion that a number of organisms 

 not commonly classed as pyogenic may, under certain 

 circumstances, assume this property. For example : 



The bacillus of typhoid fever has been found in pure 

 culture in osteomyelitis of the ribs, in acute purulent 

 otitis media, in abscess of the soft parts, in the pus 

 of empyema, and in localized fibro-peritonitis, either 

 during its course or as a sequel of typhoid fever. 



Bacillus coli has been found in pure culture in acute 

 peritonitis, in liver-abscess, in purulent inflammation 

 of the gall-bladder and ducts, and in appendicitis ; and 

 Welch 1 has found it in pure culture in fifteen different 

 inflammatory conditions. 



1 Welch : " Conditions Underlying the Infection of Wounds," Ameri- 

 can Journal of the Medical Sciences, November, 1891. 



