SURCTNA TETRAGENA. 329 



eludes that the serum does not possess any bactericidal 

 power, but that it acts through its antitoxic properties. 



Panichi employed his serum in the treatment of seven 

 cases of pneumonia. The serum was injected intrave- 

 nously, and was followed by lysis that is, there was a 

 reduction of the temperature, of the pulse, and of the 

 respiration, as well as improvement in the general ap- 

 pearance of the patient. The bright red exudate be- 

 came rusty and, later, catarrhal in character. Diminished 

 crepitation was noticed when a sufficient dose had been 

 reached (15 to 30 c.c.). Of the seven cases, six were 

 improved. In one the result was negative. In the 

 latter the treatment was undertaken at five-sevenths of 

 the total duration of the disease. The treatment of 

 human beings corresponded entirely with the results 

 of the experimental study of the serum in animals, in the 

 quantity of serum required for treatment, as well as 

 in the time period within which the injection was of 

 value. 



INFECTION WITH SARCINA TETRAGENA 

 MIGULA, 1900. 



Synonym : Micrococcus tetragenus, Gaffky, 1883. 



Should the death of the animal not occur within the 

 first twenty-eight to thirty hours after inoculation, but 

 be postponed until between the fourth and eighth day, it 

 may result from the invasion of the tissues by the organ- 

 ism now to be described, viz., sarcina tetragena. 



This organism was discovered by Gaffky, and was 

 subsequently described by Koch in the account of his 

 experiments upon tuberculosis. It is often present in 

 the saliva of healthy individuals and is commonly 



