CHAPTER XX. 



Glanders Characteristics of the disease Histological structure of the 

 glanders nodule Susceptibility of different animals to glanders 

 The bacterium of glanders; its morphological and cultural pecu- 

 liaritiesDiagnosis of glanders Mallein. 



The disease is generally known as glanders when the 

 mucous membrane of the nostrils is affected, and as farcy 

 when the subcutaneous lymphatics are the principal sites 

 of involvement. 



Though most commonly seen in the horse and ass, 

 glanders is not rarely met with in other animals, and is 

 occasionally encountered in man. When occurring 

 spontaneously in the horse its primary seat is usually 

 upon the mucous membrane of the nostrils. It appears 

 in the form of small gray nodules, about which the 

 membrane is congested and swollen. These nodules 

 ultimately coalesce to form ulcers. There is a profuse 

 slimy discharge from the nostrils during the course of the 

 disease. The primary lesion may extend from its seat in 

 the nose to the mouth, larynx, trachea, and ultimately 

 to the lungs. Its secondary manifestations are observed 

 along the lymphatics that communicate with the initial 

 focus ; in the lymphatic glands, and as metastatic foci 

 in the internal organs. Less frequently the disease is 

 seen to begin in the skin, particularly in the region of 

 the neck and breast. When in this locality the sub- 

 cutaneous lymphatics become involved, and are con- 



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