694: PHYSIOLOGY 



swelling of the ends of the long bones at the junction of the epiphysis with 

 the shaft and by softening of the bones as a whole, so that these bend under 

 the weight of the body, giving rise to bow legs, deformities of the pelvis, etc. 1 

 At the present we are justified in defining three kinds of food hormones, 

 viz. : 



(1) Fat-soluble substance A, which is contained in butter and is 

 essential to growth. This substance is also present in many green 

 vegetables. 



(2) "Water-soluble substance B, present in the outer parts of most 

 grain, in eggs, yeast, etc. The absence of this substance leads to the pro- 

 duction of beri-beri. It is sometimes known as the anti-neuritic substance. 



(3) A substance present in fresh vegetables, destroyed by boiling or 

 even by drying of the vegetables, and to a smaller extent in meat and fresh 

 milk. The absence of this substance gives rise to scurvy, so it can be spoken 

 of as an anti-scorbutic substance. 



1 Funk has suggested the name of Vitamine for these substances,' but although this 

 term is often used it is misleading, since there is no evidence that this substance as a 

 class is either basic in nature or has any relation to amines. 



