1204 PHYSIOLOGY 



glomerular transudate, in passing through the tubules, may thus be con- 

 centrated sixty to a hundred times. Since glucose is made in the body 

 and supplied to the circulating blood in proportion to the needs of the 

 body, so as to maintain its concentration in the plasma at a definite height, 

 the loss of sugar in the urine will be continued, and the percentage in the 

 plasma will not tend to diminish progressively with the increased secretion 

 of urine, as would occur for example in the case of urea. We may assume 

 that different diuretics have similar powers of paralysis on the absorptive 

 mechanisms of the tubules, either general, or confined as in the case of 

 phlorhizin to one or other of the normal constituents of the plasma. 



