88 PHILOSOPHICAL TRANSACTIONS. [aNNO 1714. 



cloud made was so great all the while, that the noise of the mischiefs done by 

 it, was as nothing. 



The Doctor gives a calculation of the possible increase of the descendants of 

 Adam ; and from this introduction proceeds to the account of some long-lived 

 persons there, and of their fruitfulness. He says it is no rare thing for an aged 

 gentlewoman to see more than 100 of her offspring. He mentions one woman 

 that had 23 children, of which IQ lived to man's estate. Another that had 27 ; 

 another 26, of which 21 were sons, one whereof was Sir William Phipps; 

 another SQ children. Here he gives several instances of persons living to above 

 100 years of age. One Clement Weaver lived to 110, his wife being upwards 

 of 100. This man, to the last year, could carry a bushel of wheat to the mill, 

 above 2 miles. He relates the case of an old man, above 100, who lost the 

 memory of several of the latter years of his life, but very well retained the re- 

 membrance of what passed in his younger days. 



An Account of the Procuring of the Small Pox by Incision, or Inoculation ; as it 

 has for some time been practised at Constantinople. Being an Extract of a 

 Letter from Emanuel Timonius,* Oxon. and Patav. M. D. S. R. S, dated Con" 

 stantinople, December, 1713. Communicated by John Woodward, M. D. and 

 S.R.S. N°339, p. 72. 



The Doctor observes, that the Circassians, Georgians, and other Asiatics, 

 have introduced this practice of procuring the small-pox by a sort of inoculation, 

 for about 40 years, among the Turks and others at Constantinople. That 

 though at first the more prudent were very cautious in the use of this practice; 

 yet the happy success it has been found to have in thousands of subjects, for 



* Emanuel Timoni was a native of Italy, but practised at Constantinople. He had travelled into 

 various parts of Europe, and had visited England. Besides this account of inoculation, he also com- 

 municated to the Royal Society a narrative of the plague, which raged at Constantinople in 1714, 

 This paper is inserted in the 31st vol. of the Phil. Trans. He had for many years enjoyed a high 

 and well-merited reputation) but meeting at length with some unexpected check, he destroyed 

 himself in a fit of desperation. 



The communications of Timoni and Pylarini on the subject of inoculation, are both inserted in 

 the same vol. of the Phil. Trans, although Timoni's appears to have been of an anterior date. 

 These two accounts may be considered as the first that were published in England, upon this in- 

 teresting subject) for although (as Dr. Woodville has remarked in his History of Inoculation, p. 71) 

 Mr. Kennedy had described, in his Essay on External Remedies, published in 1715, the manner of 

 ingrafting the small-pox 2i% practised in Turkey; yet it is evident from that author's own words at 

 p. 155 of his essay, that his knowledge on this subject was derived from Timoni, who resided at 

 Constantinople, when Mr. Kennedy visited that capital, and who had previously inoculated there his 

 two sisters. 



